KDA
- Current
- Browse
- Collections
-
For contributors
- For Authors
- Instructions to authors
- Article processing charge
- e-submission
- For Reviewers
- Instructions for reviewers
- How to become a reviewer
- Best reviewers
- For Readers
- Readership
- Subscription
- Permission guidelines
- About
- Editorial policy
Search
- Page Path
- HOME > Search
Original Articles
- Complications
- Presence of Carotid Plaque Is Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Normal Renal Function
- Da Hea Seo, So Hun Kim, Joon Ho Song, Seongbin Hong, Young Ju Suh, Seong Hee Ahn, Jeong-Taek Woo, Sei Hyun Baik, Yongsoo Park, Kwan Woo Lee, Young Seol Kim, Moonsuk Nam
- Diabetes Metab J. 2019;43(6):840-853. Published online March 12, 2019
- DOI: https://doi.org/10.4093/dmj.2018.0186
- 5,544 View
- 57 Download
- 17 Web of Science
- 16 Crossref
-
Abstract
PDF
Supplementary Material
PubReader Background Recent evidences indicate that early rapid renal function decline is closely associated with the development and progression of diabetic kidney disease. We have investigated the association between carotid atherosclerosis and rapid renal function decline in patients with type 2 diabetes mellitus and preserved renal function.
Methods In a prospective, multicenter cohort, a total of 967 patients with type 2 diabetes mellitus and preserved renal function were followed for 6 years with serial estimated glomerular filtration rate (eGFR) measurements. Common carotid intima-media thickness (CIMT) and presence of carotid plaque were assessed at baseline. Rapid renal function decline was defined as an eGFR decline >3.3% per year.
Results Over a median follow-up of 6 years, 158 participants (16.3%) developed rapid renal function decline. While there was no difference in CIMT, the presence of carotid plaque in rapid decliners was significantly higher than in non-decliners (23.2% vs. 12.2%,
P <0.001). In multivariable logistic regression analysis, presence of carotid plaque was an independent predictor of rapid renal function decline (odds ratio, 2.33; 95% confidence interval, 1.48 to 3.68;P <0.0001) after adjustment for established risk factors. The model including the carotid plaque had better performance for discrimination of rapid renal function decline than the model without carotid plaque (area under the receiver operating characteristic curve 0.772 vs. 0.744,P =0.016).Conclusion Close monitoring of renal function and early intensive management may be beneficial in patients with type 2 diabetes mellitus and carotid plaques.
-
Citations
Citations to this article as recorded by
- Impact of diabetes distress on glycemic control and diabetic complications in type 2 diabetes mellitus
Hye-Sun Park, Yongin Cho, Da Hea Seo, Seong Hee Ahn, Seongbin Hong, Young Ju Suh, Suk Chon, Jeong-Taek Woo, Sei Hyun Baik, Kwan Woo Lee, So Hun Kim
Scientific Reports.2024;[Epub] CrossRef - Correlation analysis of carotid plaque in young patients with newly diagnosed type 2 diabetes and platelet-to-lymphocyte ratio and neutrophil–lymphocyte ratio
Huijun Wen, Hai Yu
Vascular.2023; 31(1): 90. CrossRef - Diabetic vascular diseases: molecular mechanisms and therapeutic strategies
Yiwen Li, Yanfei Liu, Shiwei Liu, Mengqi Gao, Wenting Wang, Keji Chen, Luqi Huang, Yue Liu
Signal Transduction and Targeted Therapy.2023;[Epub] CrossRef - Carotid intima-media thickness and atherosclerotic plaques are associated with renal function decline: a 14-year longitudinal population-based study
Miriam Goepfert, Till Ittermann, Marcus Dörr, Nele Friedrich, Henry Völzke, Thomas Dabers, Stephan B Felix, Ulf Schminke, Sylvia Stracke, Sabrina von Rheinbaben
Nephrology Dialysis Transplantation.2023; 38(11): 2598. CrossRef - Blood pressure and vascular determinants of glomerular filtration rate decline in diabetic kidney disease
Luca Truscello, Dina Nobre, Vehashini Sabaratnam, Olivier Bonny, Grégoire Wuerzner, Michel Burnier, Fadi Fakhouri, Menno Pruijm, Anne Zanchi
Frontiers in Cardiovascular Medicine.2023;[Epub] CrossRef - Explainable Artificial Intelligence Paves the Way in Precision Diagnostics and Biomarker Discovery for the Subclass of Diabetic Retinopathy in Type 2 Diabetics
Fatma Hilal Yagin, Seyma Yasar, Yasin Gormez, Burak Yagin, Abdulvahap Pinar, Abedalrhman Alkhateeb, Luca Paolo Ardigò
Metabolites.2023; 13(12): 1204. CrossRef - Evaluation of Subclinical Vascular Disease in Diabetic Kidney Disease: A Tool for Personalization of Management of a High-Risk Population
Christodoula Kourtidou, Vasileios Rafailidis, Garyfallia Varouktsi, Efthimios Kanakis, Vassilios Liakopoulos, Timoleon-Achilleas Vyzantiadis, Maria Stangou, Smaragdi Marinaki, Konstantinos Tziomalos
Journal of Personalized Medicine.2022; 12(7): 1139. CrossRef - Prevalence and Predictors of Renal Disease in a National Representative Sample of the Romanian Adult Population: Data from the SEPHAR IV Survey
Călin Pop, Oana Florentina Gheorghe Fronea, Ioana Antonia Branea, Lucian Mihai Itu, Roxana Darabont, Irinel Parepa, Theodora Benedek, Maria Dorobantu
Diagnostics.2022; 12(12): 3199. CrossRef - Clinical features of and risk factors for normoalbuminuric diabetic kidney disease in hospitalized patients with type 2 diabetes mellitus: a retrospective cross-sectional study
Qi Dai, Nan Chen, Ling Zeng, Xin-Jie Lin, Feng-Xiu Jiang, Xiong-Jie Zhuang, Ze-Yuan Lu
BMC Endocrine Disorders.2021;[Epub] CrossRef - The Predictive Value of Carotid Ultrasonography With Cardiovascular Risk Factors—A “SPIDER” Promoting Atherosclerosis
Hongwei Li, Xiaolin Xu, Baoming Luo, Yuling Zhang
Frontiers in Cardiovascular Medicine.2021;[Epub] CrossRef - Update on pathogenesis and diagnosis flow of normoalbuminuric diabetes with renal insufficiency
Le Deng, Wenjie Li, Gaosi Xu
European Journal of Medical Research.2021;[Epub] CrossRef - Association of serum fibroblast growth factor 21 with kidney function in a population-based Chinese cohort
Rui Zhang, Yufeng Li, Xianghai Zhou, Fang Zhang, Meng Li, Simin Zhang, Xiuying Zhang, Xin Wen, Linong Ji
Medicine.2021; 100(50): e28238. CrossRef - Letter: Presence of Carotid Plaque Is Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Normal Renal Function (Diabetes Metab J 2019;43:840–53)
Min-Ji Kim, Jae-Han Jeon
Diabetes & Metabolism Journal.2020; 44(1): 201. CrossRef - Response: Presence of Carotid Plaque Is Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Normal Renal Function (Diabetes Metab J 2019;43:840–53)
Da Hea Seo, So Hun Kim, Moonsuk Nam
Diabetes & Metabolism Journal.2020; 44(1): 205. CrossRef - Serum Levels of Adipocyte Fatty Acid-Binding Protein Are Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Preserved Renal Function
Da Hea Seo, Moonsuk Nam, Mihye Jung, Young Ju Suh, Seong Hee Ahn, Seongbin Hong, So Hun Kim
Diabetes & Metabolism Journal.2020; 44(6): 875. CrossRef - Proteinuria Is Associated with Carotid Artery Atherosclerosis in Non-Albuminuric Type 2 Diabetes: A Cross-Sectional Study
Jaehyun Bae, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Byung-Wan Lee
Journal of Clinical Medicine.2020; 9(1): 136. CrossRef
- Impact of diabetes distress on glycemic control and diabetic complications in type 2 diabetes mellitus
- Clinical Diabetes & Therapeutics
- Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial
- Tae Jung Oh, Jae Myung Yu, Kyung Wan Min, Hyun Shik Son, Moon Kyu Lee, Kun Ho Yoon, Young Duk Song, Joong Yeol Park, In Kyung Jeong, Bong Soo Cha, Yong Seong Kim, Sei Hyun Baik, In Joo Kim, Doo Man Kim, Sung Rae Kim, Kwan Woo Lee, Jeong Hyung Park, In Kyu Lee, Tae Sun Park, Sung Hee Choi, Sung Woo Park
- Diabetes Metab J. 2019;43(3):276-286. Published online December 7, 2018
- DOI: https://doi.org/10.4093/dmj.2018.0051
- 7,057 View
- 99 Download
- 13 Web of Science
- 12 Crossref
-
Abstract
PDFPubReader
Background Combination of metformin to reduce the fasting plasma glucose level and an α-glucosidase inhibitor to decrease the postprandial glucose level is expected to generate a complementary effect. We compared the efficacy and safety of a fixed-dose combination of voglibose plus metformin (vogmet) with metformin monotherapy in drug-naïve newly-diagnosed type 2 diabetes mellitus.
Methods A total of 187 eligible patients aged 20 to 70 years, with a glycosylated hemoglobin (HbA1c) level of 7.0% to 11.0%, were randomized into either vogmet or metformin treatments for 24 weeks. A change in the HbA1c level from baseline was measured at week 24.
Results The reduction in the levels of HbA1c was −1.62%±0.07% in the vogmet group and −1.31%±0.07% in the metformin group (
P =0.003), and significantly more vogmet-treated patients achieved the target HbA1c levels of <6.5% (P =0.002) or <7% (P =0.039). Glycemic variability was also significantly improved with vogmet treatment, estimated by M-values (P =0.004). Gastrointestinal adverse events and hypoglycemia (%) were numerically lower in the vogmet-treated group. Moreover, a significant weight loss was observed with vogmet treatment compared with metformin (−1.63 kg vs. −0.86 kg,P =0.039).Conclusion Vogmet is a safe antihyperglycemic agent that controls blood glucose level effectively, yields weight loss, and is superior to metformin in terms of various key glycemic parameters without increasing the risk of hypoglycemia.
-
Citations
Citations to this article as recorded by- Phytochemical analysis and antihyperglycemic activity of Castilleja arvensis
Mónica Aideé Díaz-Román, Juan José Acevedo-Fernández, Gabriela Ávila-Villarreal, Elizabeth Negrete-León, A. Berenice Aguilar-Guadarrama
Fitoterapia.2024; 174: 105839. CrossRef - YAP/TAZ axis was involved in the effects of metformin on breast cancer
Yu Xu, Hongke Cai, Yuanfeng Xiong, Li Tang, Longjiang Li, Li Zhang, Yi Shen, Yongqiang Yang, Ling Lin, Jiayi Huang
Journal of Chemotherapy.2023; 35(7): 627. CrossRef - Diabetes remission: Myth or reality?
Ashok Kumar, ShubhaLaxmi Margekar, Ravi Kumar
Indian Journal of Medical Specialities.2023; 14(1): 3. CrossRef - Analysis of Reports Sent to the Portuguese Pharmacovigilance System and Published Literature Regarding the Safety of Metformin in the Elderly
Beatriz Esteves, Cristina Monteiro, Ana Paula Coelho Duarte
Healthcare.2023; 11(15): 2197. CrossRef - Rapid prediction method of α-Glycosidase inhibitory activity of Coreopsis tinctoria extract from different habitats by near infrared spectroscopy
Xiaogang He, Xiang Han, Jiaping Yu, Yulong Feng, Ganghui Chu
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2022; 268: 120601. CrossRef - Insulin autoimmune syndrome in patients with type 2 diabetes: A report of two cases
Y. Shin, T.J. Oh, S.H. Choi, H.C. Jang
Diabetes & Metabolism.2021; 47(1): 101115. CrossRef - Efficacy and Safety of Treatment with Quadruple Oral Hypoglycemic Agents in Uncontrolled Type 2 Diabetes Mellitus: A Multi-Center, Retrospective, Observational Study
Jun Sung Moon, Sunghwan Suh, Sang Soo Kim, Heung Yong Jin, Jeong Mi Kim, Min Hee Jang, Kyung Ae Lee, Ju Hyung Lee, Seung Min Chung, Young Sang Lyu, Jin Hwa Kim, Sang Yong Kim, Jung Eun Jang, Tae Nyun Kim, Sung Woo Kim, Eonju Jeon, Nan Hee Cho, Mi-Kyung Ki
Diabetes & Metabolism Journal.2021; 45(5): 675. CrossRef - Quantifying Remission Probability in Type 2 Diabetes Mellitus
Sanjay Kalra, Ganapathi Bantwal, Nitin Kapoor, Rakesh Sahay, Saptarshi Bhattacharya, Beatrice Anne, Raju A Gopal, Sunil Kota, Ashok Kumar, Ameya Joshi, Debmalya Sanyal, Mangesh Tiwaskar, Ashok Kumar Das
Clinics and Practice.2021; 11(4): 850. CrossRef - The effect of voglibose on metabolic profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of clinical trials
Peyman Nowrouzi-Sohrabi, Reza Tabrizi, Shahla Rezaei, Fatemeh Jafari, Kamran Hessami, Mehdi Abedi, Mohammad Jalali, Pedram Keshavarzi, Saeed Shahabi, Ali Asghar Kolahi, Kristin Carson-Chahhoud, Amirhossein Sahebkar, Saeid Safiri
Pharmacological Research.2020; 159: 104988. CrossRef - Role of Intestinal Microbiota in Metabolism of Voglibose In Vitro and In Vivo
Mahesh Raj Nepal, Mi Jeong Kang, Geon Ho Kim, Dong Ho Cha, Ju-Hyun Kim, Tae Cheon Jeong
Diabetes & Metabolism Journal.2020; 44(6): 908. CrossRef - Response: Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes metab J 2019;43;276-86)
Tae Jung Oh, Sung Hee Choi
Diabetes & Metabolism Journal.2019; 43(4): 547. CrossRef - Letter: Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes Metab J 2019;43;276-86)
Hannah Seok, Tae Seo Sohn
Diabetes & Metabolism Journal.2019; 43(4): 545. CrossRef
- Phytochemical analysis and antihyperglycemic activity of Castilleja arvensis
- Clinical Care/Education
- Impact of Socioeconomic Status on Health Behaviors, Metabolic Control, and Chronic Complications in Type 2 Diabetes Mellitus
- So Hun Kim, Seung Youn Lee, Chei Won Kim, Young Ju Suh, Seongbin Hong, Seong Hee Ahn, Da Hae Seo, Moon-Suk Nam, Suk Chon, Jeong-Taek Woo, Sei Hyun Baik, Yongsoo Park, Kwan Woo Lee, Young Seol Kim
- Diabetes Metab J. 2018;42(5):380-393. Published online June 29, 2018
- DOI: https://doi.org/10.4093/dmj.2017.0102
- 4,837 View
- 67 Download
- 11 Web of Science
- 15 Crossref
-
Abstract
PDFSupplementary MaterialPubReader
Background The aim of the study was to assess the impact of socioeconomic status (SES) on health behaviors, metabolic control, and chronic complications in people with type 2 diabetes mellitus (T2DM) from South Korea, a country with universal health insurance coverage and that has experienced rapid economic and social transition.
Methods A total of 3,294 Korean men and women with T2DM aged 30 to 65 years, participating in the Korean National Diabetes Program (KNDP) cohort who reported their SES and had baseline clinical evaluation were included in the current cross-sectional analysis. SES included the level of education and monthly household income.
Results Lower education level and lower income level were closely related, and both were associated with older age in men and women. Women and men with lower income and education level had higher carbohydrate and lower fat intake. After adjustment for possible confounding factors, higher education in men significantly lowered the odds of having uncontrolled hyperglycemia (glycosylated hemoglobin ≥7.5%) (odds ratio [OR], 0.63; 95% confidence interval [CI], 0.43 to 0.91 for highest education;
P trend=0.048), while higher household income in men significantly lowered the odds of having diabetic retinopathy (OR, 0.59; 95% CI, 0.37 to 0.95 for highest income level;P trend=0.048). In women, lower income was associated with a higher stress level.Conclusion Men with lower SES had higher odds of having diabetic retinopathy and uncontrolled hyperglycemia, showing the need to improve care targeted to this population.
-
Citations
Citations to this article as recorded by- A Scoping Review of Possible Solutions for Decreasing Socioeconomic Inequalities in Type 2 Diabetes Mellitus
Laleh Gharacheh, Mostafa Amini-Rarani, Amin Torabipour, Saeed Karimi
International Journal of Preventive Medicine.2024;[Epub] CrossRef - Socioeconomic status and the effect of prolonged pandemic confinement on anthropometric and glycaemic outcomes in adults with type 2 diabetes mellitus
Chandana Wijeweera, Ummul Muhfaza, Reginald V. Lord, Peter Petocz, Juliana Chen, Veronica Preda
Primary Care Diabetes.2024;[Epub] CrossRef - Income variability and incident cardiovascular disease in diabetes: a population-based cohort study
Yong-Moon Mark Park, Jong-Ha Baek, Hong Seok Lee, Tali Elfassy, Clare C Brown, Mario Schootman, Marie-Rachelle Narcisse, Seung-Hyun Ko, Pearl A McElfish, Michael R Thomsen, Benjamin C Amick, Seong-Su Lee, Kyungdo Han
European Heart Journal.2024;[Epub] CrossRef - Association of diet quality with glycemia, insulinemia, and insulin resistance in families at high risk for type 2 diabetes mellitus in Europe: Feel4 Diabetes Study
Botsi E, Karatzi K, Mavrogianni C, Kaloyan Tsochev, Esther M González-Gil, Radó S, Kivelä J, Wikström K, Cardon G, Rurik I, Liatis S, Tsvetalina Tankova, Violeta Iotova, Luis A. Moreno, Makrillakis K, Manios Y, Tsigos C
Nutrition.2023; 105: 111805. CrossRef - Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study
Hong Seok Lee, Jimin Clara Park, Inkwan Chung, Junxiu Liu, Seong-Su Lee, Kyungdo Han
Diabetes Care.2023; 46(1): 92. CrossRef - Association of birth weight with risk of diabetes mellitus in adolescence and early adulthood: analysis of the Indonesian Family Life Survey
Ratu Ayu Dewi Sartika, Fathimah Sulistyowati Sigit, Edy Purwanto, Norliyana Aris, Avliya Quratul Marjan, Wahyu Kurnia Yusrin Putra, Sutanto Priyo Hastono
Annals of Pediatric Endocrinology & Metabolism.2023; 28(4): 267. CrossRef - Effects of Diabetes Quality Assessment on Diabetes Management Behaviors Based on a Nationwide Survey
Chang Kyun Choi, Jungho Yang, Ji-An Jeong, Min-Ho Shin
International Journal of Environmental Research and Public Health.2022; 19(23): 15781. CrossRef - FOLLOW-UP ADHERENCE IN PATIENTS WITH NONPROLIFERATIVE DIABETIC RETINOPATHY PRESENTING TO AN OPHTHALMIC EMERGENCY DEPARTMENT
Arjun Watane, Meghana Kalavar, Elizabeth A. Vanner, Kara Cavuoto, Jayanth Sridhar
Retina.2021; 41(6): 1293. CrossRef - Socioeconomic disparity in global vision loss burden due to diabetic retinopathy: an analysis on time trends from 1990 to 2017
Yi Shan, Yufeng Xu, Lingxia Ye, Xiling Lin, Yaoyao Chen, Qi Miao, Juan Ye
Endocrine.2021; 73(2): 316. CrossRef - Tip 2 Diyabetli Bireylerin Hastalık Yönetiminde Karşılaştıkları Engellerin Değerlendirilmesi
Şuheda ÜSTÜNDAĞ, Nuray DAYAPOĞLU
Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi.2021; 5(3): 514. CrossRef - Socioeconomic inequalities in type 2 diabetes in employed individuals, nonworking spouses and pensioners
Batoul Safieddine, Stefanie Sperlich, Johannes Beller, Karin Lange, Jelena Epping, Juliane Tetzlaff, Fabian Tetzlaff, Siegfried Geyer
SSM - Population Health.2020; 11: 100596. CrossRef - Thirteen-year trends in the prevalence of diabetes according to socioeconomic condition and cardiovascular risk factors in a Swiss population
Carlos de Mestral, Silvia Stringhini, Idris Guessous, François R Jornayvaz
BMJ Open Diabetes Research & Care.2020; 8(1): e001273. CrossRef - Dietary Habits and Dietary Antioxidant Intake Are Related to Socioeconomic Status in Polish Adults: A Nationwide Study
Małgorzata Elżbieta Zujko, Anna Waśkiewicz, Wojciech Drygas, Alicja Cicha-Mikołajczyk, Kinga Zujko, Danuta Szcześniewska, Krystyna Kozakiewicz, Anna Maria Witkowska
Nutrients.2020; 12(2): 518. CrossRef - Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status
Bo-Yeon Kim, Jong Chul Won, Jae Hyuk Lee, Hun-Sung Kim, Jung Hwan Park, Kyoung Hwa Ha, Kyu Chang Won, Dae Jung Kim, Kyong Soo Park
Diabetes & Metabolism Journal.2019; 43(4): 487. CrossRef - Gender in Endocrine Diseases: Role of Sex Gonadal Hormones
R. Lauretta, M. Sansone, A. Sansone, F. Romanelli, M. Appetecchia
International Journal of Endocrinology.2018; 2018: 1. CrossRef
- A Scoping Review of Possible Solutions for Decreasing Socioeconomic Inequalities in Type 2 Diabetes Mellitus
- The Relationship between Diabetes Mellitus and Health-Related Quality of Life in Korean Adults: The Fourth Korea National Health and Nutrition Examination Survey (2007-2009)
- Yong Jun Choi, Min Suk Lee, So Yeon An, Tae Ho Kim, Seung Jin Han, Hae Jin Kim, Yoon-Sok Chung, Kwan Woo Lee, Dae Jung Kim
- Diabetes Metab J. 2011;35(6):587-594. Published online December 26, 2011
- DOI: https://doi.org/10.4093/dmj.2011.35.6.587
- 4,829 View
- 52 Download
- 45 Crossref
-
Abstract
PDFPubReader
Background Diabetes is a major health problem in Korea. However, interest in the quality of life in patients with diabetes is low. We examined the effects of diabetes on health-related quality of life (HRQoL) and compared it with HRQoL in the general Korean population using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) (2007-2009).
Methods Using KNHANES IV data, we compared EuroQol (EQ)-5D and EQ-visual analogue scale (VAS) scores after adjusting for sociodemographic and psychosocial factors as well as for comorbidities (hypertension, heart disease, stroke, arthritis, and chronic renal disease). Logistic regressions were used to explore determinants for the lowest quintile HRQoL scales in the diabetes group.
Results The mean age of the 14,441 enrolled subjects (6,129 men and 8,312 women) was 52.5±14.5 years. The mean EQ-5D and EQ-VAS scores were significantly lower in the diabetes group (EQ-5D. 0.87; EQ-VAS, 71.94) than in the non-diabetes group (EQ-5D, 0.94; EQ-VAS, 77.40) (
P <0.001). Self-reported depressive symptom had a significant effect on lowering the EQ-VAS (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.1 to 2.6) in the diabetes group. Stress level had a significant effect in lowering both the EQ-5D (OR, 2.0; 95% CI, 1.3 to 2.9) and the EQ-VAS (OR, 1.9; 95% CI, 1.3 to 2.9). HbA1c, diabetes duration, and treatment modalities had no significant effect on lowering HRQoL.Conclusion Diabetes was clearly associated with impaired HRQoL compared with the non-diabetic population regardless of comorbidities. Therapeutic approaches should focus much more on the subjective perception of health in patients with diabetes.
-
Citations
Citations to this article as recorded by- Understanding health‐related quality of life trajectories among older adults with diabetes mellitus: Mixed methods research
Sunhee Park, Taewha Lee
Nursing Open.2023; 10(10): 6945. CrossRef - Evaluation of the Relation between Compliance with Mediterranean Diet and Quality of Life of Patients with Type 2 Diabetes
Meltem Kudret, Fatma Nişancı Kılınç, Sevilay Karahan
Nutrition and Cancer.2023; 75(2): 562. CrossRef - The status of stigma in patients with type 2 diabetes mellitus and its association with medication adherence and quality of life in China: A cross-sectional study
Xiaoyan Li, Lingyun Wu, Jie Yun, Qiuhua Sun
Medicine.2023; 102(26): e34242. CrossRef - Factors Influencing the Subjective Health Status of Men with Insulin-treated Type 2 Diabetes Mellitus: A Secondary Analysis Using Quantile Regression Analysis
Kang Sun Lee, Hyuk Joon Kim, Young Man Kim, Hye Young Kim
Journal of Korean Academy of Fundamentals of Nursing.2023; 30(4): 530. CrossRef - Association of temporomandibular disorders and tinnitus with health‐related quality of life: A cross‐sectional study using the Fifth Korea National Health and Nutrition Examination Survey
Geon‐Sik Kong, Sook‐Hyun Lee, Kyoung Sun Park, Jae‐Heung Cho, Koh‐Woon Kim, In‐Hyuk Ha
Journal of Oral Rehabilitation.2022; 49(3): 283. CrossRef - Health-related quality of life of patients with type 2 diabetes mellitus at a tertiary care hospital in Ethiopia
Girma Tekle Gebremariam, Selam Biratu, Metasebia Alemayehu, Abraham Gebregziabiher Welie, Kebede Beyene, Beate Sander, Gebremedhin Beedemariam Gebretekle, Vijayaprakash Suppiah
PLOS ONE.2022; 17(2): e0264199. CrossRef - The role of nutritional status in the relationship between diabetes and health-related quality of life
Sohyun Park, Sukyoung Jung, Hyunsook Yoon
Nutrition Research and Practice.2022; 16(4): 505. CrossRef - Associations between Food Groups and Health-Related Quality of Life in Korean Adults
Shamirah Nabbosa, Sunghee Lee
Nutrients.2022; 14(17): 3643. CrossRef - Quality of life among adult patients living with diabetes in Rwanda: a cross-sectional study in outpatient clinics
Charilaos Lygidakis, Jean Paul Uwizihiwe, Michela Bia, Francois Uwinkindi, Per Kallestrup, Claus Vögele
BMJ Open.2021; 11(2): e043997. CrossRef - THE RELATIONSHIP BETWEEN SELF-MANAGEMENT AND QUALITY OF LIFE AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS
Ninik Ambar Sari, Ceria Nurhayati
Nurse and Health: Jurnal Keperawatan.2021; 10(2): 343. CrossRef - Measurement of health-related quality of life in patients with diabetes mellitus using EQ-5D-5L in Hong Kong, China
Eliza Lai yi Wong, Richard Huan Xu, Annie Wai ling Cheung
Quality of Life Research.2020; 29(7): 1913. CrossRef - Non-Exercise Based Estimation of Cardiorespiratory Fitness Mediates Associations between Comorbidities and Health-Related Quality of Life in Older Korean Adults with Diabetes
Inhwan Lee, Shinuk Kim, Hyunsik Kang
International Journal of Environmental Research and Public Health.2020; 17(4): 1164. CrossRef - Health related quality of life and healthcare utilization among adults with diabetes and kidney and eye complications in the United States
Abdulkarim M. Meraya, Monira Alwhaibi
Health and Quality of Life Outcomes.2020;[Epub] CrossRef - Limitations of Deep Learning Attention Mechanisms in Clinical Research: Empirical Case Study Based on the Korean Diabetic Disease Setting
Junetae Kim, Sangwon Lee, Eugene Hwang, Kwang Sun Ryu, Hanseok Jeong, Jae Wook Lee, Yul Hwangbo, Kui Son Choi, Hyo Soung Cha
Journal of Medical Internet Research.2020; 22(12): e18418. CrossRef - Predictors of Health-Related Quality of Life in Korean Adults with Diabetes Mellitus
Mihyun Jeong
International Journal of Environmental Research and Public Health.2020; 17(23): 9058. CrossRef - Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
Diabetes & Metabolism Journal.2018; 42(5): 415. CrossRef - Does ancestry influence health-related quality of life in type 1 diabetes patients? A nationwide study in Brazil
Deborah Conte Santos, Marcela Haas Pizarro, Bianca S. V. Barros, Laura G. Nunes de Melo, Luis Cristovão Porto, Dayse A. Silva, Marilia Brito Gomes
Acta Diabetologica.2018; 55(4): 377. CrossRef - Lipid profiles in adolescents with and without asthma: Korea National Health and nutrition examination survey data
Sun-Hye Ko, Jaewook Jeong, Myong Ki Baeg, Kyung-Do Han, Hwan Soo Kim, Jong-seo Yoon, Hyun Hee Kim, Jin Tack Kim, Yoon Hong Chun
Lipids in Health and Disease.2018;[Epub] CrossRef - Evaluation of Health Status of Type 2 Diabetes Outpatients Receiving Care in a Tertiary Hospital in Nigeria
Maxwell Ogochukwu Adibe, Chibueze Anosike, Sunday Odunke Nduka, Abdulmuminu Isah
PharmacoEconomics - Open.2018; 2(3): 337. CrossRef - Association between chronic conditions and health-related quality of life: differences by level of urbanization in Peru
Alvaro Taype-Rondan, Elizabeth Sarah Abbs, Maria Lazo-Porras, William Checkley, Robert H. Gilman, Liam Smeeth, J. Jaime Miranda, Antonio Bernabe-Ortiz
Quality of Life Research.2017; 26(12): 3439. CrossRef - The impact of weight misperception on health-related quality of life in Korean adults (KNHANES 2007–2014): a community-based cross-sectional study
Susan Park, Sejin Lee, Jinseub Hwang, Jin-Won Kwon
BMJ Open.2017; 7(6): e016098. CrossRef - Self-efficacy and self-care behaviours among adults with type 2 diabetes
Melba Sheila D'Souza, Subrahmanya Nairy Karkada, Kader Parahoo, Ramesh Venkatesaperumal, Susan Achora, Arcalyd Rose R. Cayaban
Applied Nursing Research.2017; 36: 25. CrossRef - Factors associated with health-related quality of life in Koreans aged over 50 Years: the fourth and fifth Korea National Health and Nutrition Examination Survey
Kyoung Min Kwon, Jung Soo Lee, Na Eun Jeon, Yeo Hyung Kim
Health and Quality of Life Outcomes.2017;[Epub] CrossRef - Quality of Life in Patients with Osteoporotic Vertebral Compression Fractures
Ho Jin Jung, Ye-Soo Park, Hyoung-Yeon Seo, Jae-Chul Lee, Ki-Chan An, Jin-Hyok Kim, Byung-Joon Shin, Tae Wook Kang, Si Young Park
Journal of Bone Metabolism.2017; 24(3): 187. CrossRef - Health Related Quality of Life among Omani Men and Women with Type 2 Diabetes
Melba Sheila D’Souza, Ramesh Venkatesaperumal, Susan D. Ruppert, Subrahmanya Nairy Karkada, Devakirubai Jacob
Journal of Diabetes Research.2016; 2016: 1. CrossRef - Heavy Alcohol Consumption with Alcoholic Liver Disease Accelerates Sarcopenia in Elderly Korean Males: The Korean National Health and Nutrition Examination Survey 2008-2010
Do Seon Song, U Im Chang, Sooa Choi, Yun Duk Jung, Kyungdo Han, Seung-Hyun Ko, Yu-Bae Ahn, Jin Mo Yang, Masaki Mogi
PLOS ONE.2016; 11(9): e0163222. CrossRef - Negative effect of a previous diagnosis of diabetes on quality of life in a Japanese population: The Gifu Diabetes Study
Yukiko Nonoyama, Mayumi Yamamoto, Shino Oba, Chisato Nagata, Kazuki Matsui, Jun Takeda
Diabetology International.2016; 7(2): 148. CrossRef - The impact of type 2 diabetes on health related quality of life in Bangladesh: results from a matched study comparing treated cases with non-diabetic controls
Novie Safita, Sheikh Mohammed Shariful Islam, Clara K. Chow, Louis Niessen, Andreas Lechner, Rolf Holle, Michael Laxy
Health and Quality of Life Outcomes.2016;[Epub] CrossRef - Utilities for Type 2 Diabetes Treatment-Related Attributes in a South Korean and Taiwanese Population
Narayan Rajan, Kristina S. Boye, Meaghan Gibbs, Yoon Ji Lee, Peter Davey, Mark Ball, Steve M. Babineaux
Value in Health Regional Issues.2016; 9: 67. CrossRef - Knowledge, attitudes, and quality of life of type 2 diabetes patients in Riyadh, Saudi Arabia
IbrahimSuliman Al-Aboudi, MohammedAzmi Hassali, AsrulAkmal Shafie
Journal of Pharmacy And Bioallied Sciences.2016; 8(3): 195. CrossRef - Low muscle mass is associated with metabolic syndrome only in nonobese young adults: the Korea National Health and Nutrition Examination Survey 2008-2010
Byung Chul Kim, Mee Kyoung Kim, Kyungdo Han, Sae-Young Lee, Seung-Hwan Lee, Seung-Hyun Ko, Hyuk-Sang Kwon, Anwar T. Merchant, Hyeon Woo Yim, Won-Chul Lee, Yong Gyu Park, Yong-Moon Park
Nutrition Research.2015; 35(12): 1070. CrossRef - Insulin Resistance Is Associated with Intraocular Pressure Elevation in a Non-Obese Korean Population
Yoon Hong Chun, Kyungdo Han, Shin Hae Park, Kyung-Min Park, Hyeon Woo Yim, Won-Chul Lee, Yong Gyu Park, Yong-Moon Park, Stephen L. Atkin
PLoS ONE.2015; 10(1): e112929. CrossRef - Sarcopenia as a Determinant of Blood Pressure in Older Koreans: Findings from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2008–2010
Kyungdo Han, Yu-Mi Park, Hyuk-Sang Kwon, Seung-Hyun Ko, Seung-Hwan Lee, Hyeon Woo Yim, Won-Chul Lee, Yong Gyu Park, Mee Kyoung Kim, Yong-Moon Park, Yan Li
PLoS ONE.2014; 9(1): e86902. CrossRef - Suicidal ideation and suicide attempts among diabetes mellitus: The Korea National Health and Nutrition Examination Survey (KNHANES IV, V) from 2007 to 2012
Jae Ho Chung, Kitae Moon, Do Hyung Kim, Joo-Won Min, Tae Ho Kim, Hee-Jin Hwang
Journal of Psychosomatic Research.2014; 77(6): 457. CrossRef - Diabetes and Depressive Symptoms in Korean Women: The Fifth Korean National Health and Nutrition Examination Survey (2010-2011)
Han Na Sung, Hong Seok Chae, Eung Soo Kim, Jong Sung Kim
Korean Journal of Family Medicine.2014; 35(3): 127. CrossRef - Factors Associated with Hemorrhoids in Korean Adults: Korean National Health and Nutrition Examination Survey
Jong-Hyun Lee, Hyo-Eun Kim, Ji-Hun Kang, Jin-Young Shin, Yun-Mi Song
Korean Journal of Family Medicine.2014; 35(5): 227. CrossRef - The Health Technology Assessment Environment in Mainland China, Japan, South Korea, and Taiwan—Implications for the Evaluation of Diabetes Mellitus Therapies
Tessa Kennedy-Martin, Beth D. Mitchell, Kristina S. Boye, Wen Chen, Bradley H. Curtis, Jennifer A. Flynn, Shunya Ikeda, Li Liu, Yen Huei Tarn, Bong-Min Yang, Emmanuel Papadimitropoulos
Value in Health Regional Issues.2014; 3: 108. CrossRef - Can “Healthy” Normal Alanine Aminotransferase Levels Identify the Metabolically Obese Phenotype? Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
Hee Yeon Kim, Chang Wook Kim, Chang Don Lee, Jong Young Choi, Chung-Hwa Park, Si Hyun Bae, Seung Kew Yoon, Kyungdo Han, Yong-Moon Park
Digestive Diseases and Sciences.2014; 59(6): 1330. CrossRef - The impact of new screen-detected and previously known type 2 diabetes on health-related quality of life: a population-based study in Qingdao, China
Yanlei Zhang, Jianping Sun, Zengchang Pang, Xiaoyong Wang, Weiguo Gao, Feng Ning, Jie Ren, Anil Kapur, Harri Sintonen, Qing Qiao
Quality of Life Research.2014; 23(8): 2319. CrossRef - Increasing achievement of the target goals for glycemic, blood pressure and lipid control for adults with diagnosed diabetes in Korea
Sung Hoon Yu, Jun Goo Kang, Yoo‐Cheol Hwang, Kyu Jeung Ahn, Hyung Joon Yoo, Hong Yup Ahn, Sung Woo Park, Cheol‐Young Park
Journal of Diabetes Investigation.2013; 4(5): 460. CrossRef - Psychosocial needs of cancer patients and related factors: a multi‐center, cross‐sectional study in Korea
Kyung‐Hyun Choi, Jae‐Hyun Park, Jong‐Hyock Park, Joo‐Sung Park
Psycho-Oncology.2013; 22(5): 1073. CrossRef - Correlates of health-related quality of life in French people with type 2 diabetes
I. Bourdel-Marchasson, C. Druet, C. Helmer, E. Eschwege, P. Lecomte, M. Le-Goff, A.J. Sinclair, A. Fagot-Campagna
Diabetes Research and Clinical Practice.2013; 101(2): 226. CrossRef - Diet Therapy in Patients of Diabetic Nephropathy
Ji-Youn Kim
The Journal of Korean Diabetes.2013; 14(1): 27. CrossRef - Health‐related quality of life among Tianjin Chinese patients with type 2 diabetes: A cross‐sectional survey
Ji‐Yan Cong, Yue Zhao, Qun‐Yan Xu, Chun‐De Zhong, Qiu‐Ling Xing
Nursing & Health Sciences.2012; 14(4): 528. CrossRef - Effects of Frequency of Follow-Up on Quality of Life of Type 2 Diabetes Patients on Oral Hypoglycemics
Ming Hu, Zhiguang Zhou, Fang Zeng, Zhenqiu Sun
Diabetes Technology & Therapeutics.2012; 14(9): 777. CrossRef
- Understanding health‐related quality of life trajectories among older adults with diabetes mellitus: Mixed methods research
Review
- Costs of Diabetes Mellitus in Korea
- Kwan Woo Lee
- Diabetes Metab J. 2011;35(6):567-570. Published online December 26, 2011
- DOI: https://doi.org/10.4093/dmj.2011.35.6.567
- 9,802 View
- 35 Download
- 22 Crossref
-
Abstract
PDFPubReader
Outcome research focusing on the economics of the medical field began in the mid-1990s and has included studies about costs, cost effectiveness, and policies. According to the American Diabetes Association, the total estimated cost of diabetes in 2007 was $174 billion. The economic burden of patients with diabetes in Canada is expected to be about $12.2 billion in 2010. Recent Korean studies have analyzed the expenses associated with type 2 diabetes for patients in selected general hospitals. Type 2 diabetic patients without complications cost approximately 1,184,563 won (the equivalent of US $1,184) per patient for healthcare annually. In contrast, patients with microvascular disease due to diabetic complications cost up to 4.7 times that amount, and patients with macrovascular disease incur up to 10.7 times the annual costs for patients without diabetic complications. Diabetic complications ultimately impact the quality of life for patients and patient mortality, and are associated with higher direct medical expenses for patients. To avoid increased medical costs, appropriate management techniques must be implemented to ensure timely care for patients with diabetes.
-
Citations
Citations to this article as recorded by- Effect of Mori ramulus on the postprandial blood glucose levels and inflammatory responses of healthy subjects subjected to an oral high-fat/sucrose challenge: A double-blind, randomized, crossover clinical trial
Soo-yeon Park, Oran Kwon, Ji Yeon Kim
Biomedicine & Pharmacotherapy.2022; 146: 112552. CrossRef - Healthcare resource utilization in patients treated with empagliflozin in East Asia
Wayne H‐H Sheu, Yutaka Seino, Elise Chia‐Hui Tan, Daisuke Yabe, Kyoung Hwa Ha, Masaomi Nangaku, Wook‐Jin Chung, Koichi Node, Atsutaka Yasui, Wei‐Yu Lei, Sunwoo Lee, Anastasia Ustyugova, Riho Klement, Anouk Deruaz‐Luyet, Moe H Kyaw, Dae Jung Kim
Journal of Diabetes Investigation.2022; 13(5): 810. CrossRef - Effects of Jerusalem Artichoke Extract and Inulin on Blood Glucose Levels and Insulin Secretion in Streptozotocin Induced Diabetic Mice
Seung Hee Kim, Byung Ki Kim, Boo Yeun Park, Jung Min Kim, Young Jik Lee, Mi Kyung Lee, Sung-Tae Yee, Mi Yeon Kang
The Journal of Korean Diabetes.2021; 22(1): 60. CrossRef - Hospital-Based Korean Diabetes Prevention Study: A Prospective, Multi-Center, Randomized, Open-Label Controlled Study
Sang Youl Rhee, Suk Chon, Kyu Jeung Ahn, Jeong-Taek Woo
Diabetes & Metabolism Journal.2019; 43(1): 49. CrossRef - Cost analysis of type 2 diabetes mellitus treatment in economically developed countries
Sara Ramzan, Peter Timmins, Syed Shahzad Hasan, Zaheer-Ud-Din Babar
Expert Review of Pharmacoeconomics & Outcomes Research.2019; 19(1): 5. CrossRef - High hemoglobin levels are associated with decreased risk of diabetic retinopathy in Korean type 2 diabetes
Min-Kyung Lee, Kyung-Do Han, Jae-Hyuk Lee, Seo-Young Sohn, Jee-Sun Jeong, Mee-Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
Scientific Reports.2018;[Epub] CrossRef - Glucose Control in Intensive Care Unit Patients: Recent Updates
Sang Youl Rhee
Journal of Neurocritical Care.2018; 11(2): 81. CrossRef - Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient‐ and physician‐related factors): A prospective observational DIPP‐FACTOR study in Korea
Sin Gon Kim, Nam Hoon Kim, Bon Jeong Ku, Ho Sang Shon, Doo Man Kim, Tae Sun Park, Yong‐Seong Kim, In Joo Kim, Dong Seop Choi
Journal of Diabetes Investigation.2017; 8(3): 346. CrossRef - Community-based randomized controlled trial of diabetes prevention study for high-risk individuals of type 2 diabetes: lifestyle intervention using web-based system
Seon-Ah Cha, Sun-Young Lim, Kook-Rye Kim, Eun-Young Lee, Borami Kang, Yoon-Hee Choi, Kun-Ho Yoon, Yu-Bae Ahn, Jin-Hee Lee, Seung-Hyun Ko
BMC Public Health.2017;[Epub] CrossRef - Assessment of hospital length of stay and direct costs of type 2 diabetes in Hubei Province, China
Dajie Chen, Shuai Liu, Xiaodong Tan, Qihan Zhao
BMC Health Services Research.2017;[Epub] CrossRef - Can the Direct Medical Cost of Chronic Disease Be Transferred across Different Countries? Using Cost-of-Illness Studies on Type 2 Diabetes, Epilepsy and Schizophrenia as Examples
Lan Gao, Hao Hu, Fei-Li Zhao, Shu-Chuen Li, Terence J Quinn
PLOS ONE.2016; 11(1): e0147169. CrossRef - Effects of mulberry leaf extract on blood glucose and serum lipid profiles in patients with type 2 diabetes mellitus: A systematic review
Seung-Ok Shin, Hyun-Ju Seo, Hyunyoung Park, Hyun Jin Song
European Journal of Integrative Medicine.2016; 8(5): 602. CrossRef - Current Status of Management in Type 2 Diabetes Mellitus at General Hospitals in South Korea
Jin-Hee Jung, Jung-Hwa Lee, Jin-Won Noh, Jeong-Eun Park, Hee-Sook Kim, Joo-Wha Yoo, Bok-Rye Song, Jeong-rim Lee, Myeong-Hee Hong, Hyang-Mi Jang, Young Na, Hyun-Joo Lee, Jeong-Mi Lee, Yang-Gyo Kang, Sun-Young Kim, Kang-Hee Sim
Diabetes & Metabolism Journal.2015; 39(4): 307. CrossRef - It's Still Not Too Late to Make a Change: Current Status of Glycemic Control in Korea
Sang Yong Kim
Diabetes & Metabolism Journal.2014; 38(3): 194. CrossRef - Preserve Common Limb in Duodenal–Jejunal Bypass Surgery Benefits Rats with Type 2-Like Diabetes
Shi-Yun Zhang, Xue-Jun Sun, Jian-Bao Zheng, Wei Wang, Dong Liu, Nan-Zheng Chen, Sai He, Xiong-Wei Huo, Wanli Smith
Obesity Surgery.2014; 24(3): 405. CrossRef - Increased Risk of Diabetes Development in Subjects with the Hypertriglyceridemic Waist Phenotype: A 4-Year Longitudinal Study
Ki Joong Han, Shin Yeoung Lee, Nam Hee Kim, Hyun Beom Chae, Tae Hoon Lee, Choel Min Jang, Kyung Mo Yoo, Hae Jung Park, Min Kyung Lee, Won Seon Jeon, Se Eun Park, Cheol-Young Park, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Eun-Jung Rhee
Endocrinology and Metabolism.2014; 29(4): 514. CrossRef - Clinical and Economic Outcomes in Medication-Adherent and -Nonadherent Patients With Type 2 Diabetes Mellitus in the Republic of Korea
So-Yeon An, Hae Jin Kim, Ki Hong Chun, Tae Ho Kim, Ja Young Jeon, Dae Jung Kim, Seung Jin Han, Young Seol Kim, Jeong Taek Woo, Kyu Jeung Ahn, Yongsoo Park, Moonsuk Nam, Sei Hyun Baik, Kwan-Woo Lee
Clinical Therapeutics.2014; 36(2): 245. CrossRef - Comparison of Two Creatinine-Based Equations for Predicting Decline in Renal Function in Type 2 Diabetic Patients with Nephropathy in a Korean Population
Eun Young Lee, Young-Mi Lee, Kyu Hun Choi, Hyun Chul Lee, Byung-Wan Lee, Beom Seok Kim
International Journal of Endocrinology.2013; 2013: 1. CrossRef - Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes
Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Ihn-Ho Cho, Hyoung Woo Lee
Diabetes & Metabolism Journal.2013; 37(1): 54. CrossRef - Severe Hypoglycemia Is a Serious Complication and Becoming an Economic Burden in Diabetes
Won Chul Ha, Su Jin Oh, Ji Hyun Kim, Jung Min Lee, Sang Ah Chang, Tae Seo Sohn, Hyun Shik Son
Diabetes & Metabolism Journal.2012; 36(4): 280. CrossRef - Severe Hypoglycemia in Patients with Diabetes
Jae Seung Yun, Seung-Hyun Ko
Diabetes & Metabolism Journal.2012; 36(4): 273. CrossRef - Intervention Strategies for Older Adults with Diabetes
Sung-Chul Lim
Journal of Korean Diabetes.2012; 13(1): 52. CrossRef
- Effect of Mori ramulus on the postprandial blood glucose levels and inflammatory responses of healthy subjects subjected to an oral high-fat/sucrose challenge: A double-blind, randomized, crossover clinical trial
Original Articles
- Prevalence of Chronic Complications in Korean Patients with Type 2 Diabetes Mellitus Based on the Korean National Diabetes Program
- Sang Youl Rhee, Suk Chon, Mi Kwang Kwon, Ie Byung Park, Kyu Jeung Ahn, In Ju Kim, Sung-Hoon Kim, Hyoung Woo Lee, Kyung Soo Koh, Doo Man Kim, Sei Hyun Baik, Kwan Woo Lee, Moon Suk Nam, Yong Soo Park, Jeong-taek Woo, Young Seol Kim
- Diabetes Metab J. 2011;35(5):504-512. Published online October 31, 2011
- DOI: https://doi.org/10.4093/dmj.2011.35.5.504
- 4,565 View
- 39 Download
- 52 Crossref
-
Abstract
PDFPubReader
Background The Korean National Diabetes Program (KNDP) cohort study is performing an ongoing large-scale prospective multicenter investigation to discover the pathogenesis of type 2 diabetes in Korean patients. This study was performed to examine the prevalence of chronic complications in patients with type 2 diabetes among those registered in the KNDP cohort within the past 4 years.
Methods This study was performed between June 2006 and September 2009 at 13 university hospitals and included 4,265 KNDP cohort participants. Among the participants, the crude prevalence of microvascular and macrovascular diseases of those checked for diabetes-related complications was determined, and the adjusted standard prevalence and standardization of the general population prevalence ratio (SPR) was estimated based on the 2005 Korean National Health and Nutrition Examination Survey (KNHANES) population demographics.
Results Among the KNDP registrants, 43.2% had hypertension, 34.8% had dyslipidemia, 10.8% had macrovascular disease, and 16.7% had microvascular disease. The SPR of the KNDP registrants was significantly higher than that of the KNHANES subjects after adjusting for demographics in the KNHANES 2005 population. However, with the exception of cardiovascular disease in females, the standardized prevalence for the most complicated items in the survey was significantly higher than that in the KNHANES subjects.
Conclusion The prevalence of macrovascular disease and peripheral vascular disease were significantly higher in Korean patients with type 2 diabetes than in the normal population. However, no significant difference was noted in the prevalence of cardiovascular disease in females.
-
Citations
Citations to this article as recorded by- Impact of diabetes distress on glycemic control and diabetic complications in type 2 diabetes mellitus
Hye-Sun Park, Yongin Cho, Da Hea Seo, Seong Hee Ahn, Seongbin Hong, Young Ju Suh, Suk Chon, Jeong-Taek Woo, Sei Hyun Baik, Kwan Woo Lee, So Hun Kim
Scientific Reports.2024;[Epub] CrossRef - Clinical and economic impact of changing reimbursement criteria for statin treatment among patients with type 2 diabetes mellitus in South Korea
Siin Kim, Kyungseon Choi, Ji-yool Kim, Hae Sun Suh
Frontiers in Pharmacology.2022;[Epub] CrossRef - The Promising First Cohort Study in Korean Patients with Obesity and Overweight: Gangwon Obesity and Metabolic Syndrome Study
Eun-Jung Rhee
Journal of Obesity & Metabolic Syndrome.2022; 31(4): 285. CrossRef - Impact of noncommunicable disease conditions and physical burden on intent to leave midwifery in Hungary
Krisztina Éles Gebriné, Kinga Lampek, Péter Takács, Miklós Zrínyi, Attila Sárváry, Andrea Sárváry
Kontakt.2021; 23(1): 45. CrossRef - Dietary glutamic acid and aspartic acid as biomarkers for predicting diabetic retinopathy
So Young Park, Jieun Kim, Jung Il Son, Sang Youl Rhee, Do-Yeon Kim, Suk Chon, Hyunjung Lim, Jeong-Taek Woo
Scientific Reports.2021;[Epub] CrossRef - Time to Reach Target Glycosylated Hemoglobin Is Associated with Long-Term Durable Glycemic Control and Risk of Diabetic Complications in Patients with Newly Diagnosed Type 2 Diabetes Mellitus: A 6-Year Observational Study (Diabetes Metab J 2021;45:368-78)
Ja Young Jeon
Diabetes & Metabolism Journal.2021; 45(4): 613. CrossRef - Time to Reach Target Glycosylated Hemoglobin Is Associated with Long-Term Durable Glycemic Control and Risk of Diabetic Complications in Patients with Newly Diagnosed Type 2 Diabetes Mellitus: A 6-Year Observational Study (Diabetes Metab J 2021;45:368-78)
Kyoung Jin Kim, Jimi Choi, Jae Hyun Bae, Kyeong Jin Kim, Hye Jin Yoo, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Sin Gon Kim, Nam Hoon Kim
Diabetes & Metabolism Journal.2021; 45(4): 617. CrossRef - Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes
Sang Ouk Chin, In Gyoon Ha, Sang Youl Rhee, Su Jin Jeong, Suk Chon, Sung Hoon Kim, Kyu Jeung Ahn, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Jeong Taek Woo
International Journal of Endocrinology.2020; 2020: 1. CrossRef - Perioperative anesthetic management of patients with diabetes mellitus: focused on blood glucose control
Hyungseok Seo
Journal of the Korean Medical Association.2020; 63(9): 526. CrossRef - Predicting Old-age Mortality Using Principal Component Analysis: Results from a National Panel Survey in Korea
Jaeyong Shin, Kwang-Soo Lee, Jae-Hyun Kim
Medicina.2020; 56(7): 360. CrossRef - A relationship between endoscopic findings
and diabetic regulation, and complications in patients with diabetes mellitus
Sevki Konur
Archives of Medical Science – Civilization Diseases.2020; 5(1): 53. CrossRef - Randomized control trial comparing the effect of cilostazol and aspirin on changes in carotid intima-medial thickness
Sangmo Hong, Munsuk Nam, Bertis B. Little, Seihyun Paik, Kwanwoo Lee, Jungtaek Woo, Dooman Kim, Jungoo Kang, Minyoung Chun, Yongsoo Park
Heart and Vessels.2019; 34(11): 1758. CrossRef - Genome‐wide association study identifies new susceptibility loci for diabetic nephropathy in Korean patients with type 2 diabetes mellitus
Kyung H. Jeong, Jin S. Kim, Jeong‐Taek Woo, Sang Y. Rhee, Yu H. Lee, Yang G. Kim, Ju‐Young Moon, Su K. Kim, Sun W. Kang, Sang H. Lee, Yeong H. Kim
Clinical Genetics.2019; 96(1): 35. CrossRef - Presence of Carotid Plaque Is Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Normal Renal Function
Da Hea Seo, So Hun Kim, Joon Ho Song, Seongbin Hong, Young Ju Suh, Seong Hee Ahn, Jeong-Taek Woo, Sei Hyun Baik, Yongsoo Park, Kwan Woo Lee, Young Seol Kim, Moonsuk Nam
Diabetes & Metabolism Journal.2019; 43(6): 840. CrossRef - The relationship between demographic and anthropometric characteristics and diabetic complications and number of hospitalizations in hospitalized diabetic patients
Yusuf Kayar, Mehmet Agin
Archives of Medical Science – Civilization Diseases.2019; 4(1): 7. CrossRef - Importance of family history of diabetes in computing a diabetes risk score in Korean prediabetic population
Morena Ustulin, Sang Youl Rhee, Suk Chon, Kyu Keung Ahn, Ji Eun Lim, Bermseok Oh, Sung-Hoon Kim, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Young Seol Kim, Jeong-Taek Woo
Scientific Reports.2018;[Epub] CrossRef - Characteristics of frequent emergency department users with type 2 diabetes mellitus in Korea
Morena Ustulin, Junghoon Woo, Jeong‐taek Woo, Sang Youl Rhee
Journal of Diabetes Investigation.2018; 9(2): 430. CrossRef - Implementation of the Chronic Disease Care System and its association with health care costs and continuity of care in Korean adults with type 2 diabetes mellitus
Woorim Kim, Yoon Soo Choy, Sang Ah Lee, Eun-Cheol Park
BMC Health Services Research.2018;[Epub] CrossRef - Long‐term effects on glycaemic control and β‐cell preservation of early intensive treatment in patients with newly diagnosed type 2 diabetes: A multicentre randomized trial
Suk Chon, Sang Youl Rhee, Kyu Jeung Ahn, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Soon Jib Yoo, Gwanpyo Koh, Dae Ho Lee, Young Seol Kim, Jeong‐Taek Woo
Diabetes, Obesity and Metabolism.2018; 20(5): 1121. CrossRef - Cardio-Ankle Vascular Index as a Surrogate Marker of Early Atherosclerotic Cardiovascular Disease in Koreans with Type 2 Diabetes Mellitus
So Young Park, Sang Ook Chin, Sang Youl Rhee, Seungjoon Oh, Jeong-Taek Woo, Sung Woon Kim, Suk Chon
Diabetes & Metabolism Journal.2018; 42(4): 285. CrossRef - Metformin reduces the risk of cancer in patients with type 2 diabetes
Hae Jin Kim, SooJin Lee, Ki Hong Chun, Ja Young Jeon, Seung Jin Han, Dae Jung Kim, Young Seol Kim, Jeong-Taek Woo, Moon-Suk Nam, Sei Hyun Baik, Kyu Jeung Ahn, Kwan Woo Lee
Medicine.2018; 97(8): e0036. CrossRef - Impact of Socioeconomic Status on Health Behaviors, Metabolic Control, and Chronic Complications in Type 2 Diabetes Mellitus
So Hun Kim, Seung Youn Lee, Chei Won Kim, Young Ju Suh, Seongbin Hong, Seong Hee Ahn, Da Hae Seo, Moon-Suk Nam, Suk Chon, Jeong-Taek Woo, Sei Hyun Baik, Yongsoo Park, Kwan Woo Lee, Young Seol Kim
Diabetes & Metabolism Journal.2018; 42(5): 380. CrossRef - Failure of monotherapy in clinical practice in patients with type 2 diabetes: The Korean National Diabetes Program
Ja Young Jeon, Soo Jin Lee, Sieun Lee, Soo Jin Kim, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Young Seol Kim, Jeong Taek Woo, Kyu Jeung Ahn, Moonsuk Nam, Sei Hyun Baik, Yongsoo Park, Kwan‐Woo Lee
Journal of Diabetes Investigation.2018; 9(5): 1144. CrossRef - Prediction of Coronary Heart Disease Risk in Korean Patients with Diabetes Mellitus
Bo Kyung Koo, Sohee Oh, Yoon Ji Kim, Min Kyong Moon
Journal of Lipid and Atherosclerosis.2018; 7(2): 110. CrossRef - Diagnosis and Management of Diabetic Foot
Chang Won Lee
The Journal of Korean Diabetes.2018; 19(3): 168. CrossRef - Clinical characteristics and risk factors for retinal diabetic neurodegeneration in type 2 diabetes
Kiyoung Kim, Eung Suk Kim, Sang Youl Rhee, Suk Chon, Jeong-taek Woo, Seung-Young Yu
Acta Diabetologica.2017; 54(11): 993. CrossRef - Features of Long-Standing Korean Type 2 Diabetes Mellitus Patients with Diabetic Retinopathy: A Study Based on Standardized Clinical Data
Sejeong Park, Sang Youl Rhee, Su Jin Jeong, Kiyoung Kim, Suk Chon, Seung-Young Yu, Jeong-Taek Woo
Diabetes & Metabolism Journal.2017; 41(5): 393. CrossRef - Clinical heterogeneity of type 1 diabetes (T1D) found in Asia
Yongsoo Park, Kupper A. Wintergerst, Zhiguang Zhou
Diabetes/Metabolism Research and Reviews.2017;[Epub] CrossRef - Response: Features of Long-Standing Korean Type 2 Diabetes Mellitus Patients with Diabetic Retinopathy: A Study Based on Standardized Clinical Data (Diabetes Metab J 2017;41:393-404)
Sang Youl Rhee, Jeong-Taek Woo
Diabetes & Metabolism Journal.2017; 41(6): 494. CrossRef - Current status of managing diabetes mellitus in Korea
Kyoung Hwa Ha, Dae Jung Kim
The Korean Journal of Internal Medicine.2016; 31(5): 845. CrossRef - Hypoglycemia is associated with dementia in elderly patients with type 2 diabetes mellitus: An analysis based on the Korea National Diabetes Program Cohort
Sang Ouk Chin, Sang Youl Rhee, Suk Chon, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Ki Hong Chun, Jeong-taek Woo, Young Seol Kim
Diabetes Research and Clinical Practice.2016; 122: 54. CrossRef - Relationship between fruit and fish intakes and cardiovascular disease risk factors in Korean women with type 2 diabetes mellitus: Based on the 4th and 5th Korea National Health and Nutrition Examination Surveys
Ji Soo Oh, Hyesook Kim, Ki Nam Kim, Namsoo Chang
Journal of Nutrition and Health.2016; 49(5): 304. CrossRef - Hypoglycemia and Medical Expenses in Patients with Type 2 Diabetes Mellitus: An Analysis Based on the Korea National Diabetes Program Cohort
Sang Youl Rhee, Soo Min Hong, Suk Chon, Kyu Jeung Ahn, Sung Hoon Kim, Sei Hyun Baik, Yong Soo Park, Moon Suk Nam, Kwan Woo Lee, Jeong-Taek Woo, Young Seol Kim, Zhengdong Zhang
PLOS ONE.2016; 11(2): e0148630. CrossRef - Elevated lipoprotein(a) levels predict cardiovascular disease in type 2 diabetes mellitus: a 10-year prospective cohort study
Tae-Seok Lim, Jae-Seung Yun, Seon-Ah Cha, Ki-Ho Song, Ki-Dong Yoo, Yu-Bae Ahn, Yong-Moon Park, Seung-Hyun Ko
The Korean Journal of Internal Medicine.2016; 31(6): 1110. CrossRef - Low Economic Status Is Identified as an Emerging Risk Factor for Diabetes Mellitus in Korean Men Aged 30 to 59 Years in Korean National Health and Nutrition Examination Survey 2008 to 2010
Bo Kyung Koo, Sang Wan Kim, Ka Hee Yi, Min Kyong Moon
Diabetes & Metabolism Journal.2015; 39(2): 137. CrossRef - Assessment of glycemic control in patients with type 2 diabetes mellitus treated with metformin–sulfonylurea combination: Results of a multicenter, cross‐sectional, observational study in Korea
Sin Gon Kim, Jong Ryeal Hahm, Duk Kyu Kim, Sung Rae Cho, Dong Seop Choi
Journal of Diabetes Investigation.2015; 6(3): 317. CrossRef - Clinical and Economic Outcomes in Medication-Adherent and -Nonadherent Patients With Type 2 Diabetes Mellitus in the Republic of Korea
So-Yeon An, Hae Jin Kim, Ki Hong Chun, Tae Ho Kim, Ja Young Jeon, Dae Jung Kim, Seung Jin Han, Young Seol Kim, Jeong Taek Woo, Kyu Jeung Ahn, Yongsoo Park, Moonsuk Nam, Sei Hyun Baik, Kwan-Woo Lee
Clinical Therapeutics.2014; 36(2): 245. CrossRef - Serum Magnesium Level Is Associated with Type 2 Diabetes in Women with a History of Gestational Diabetes Mellitus: The Korea National Diabetes Program Study
Sae Jeong Yang, Soon Young Hwang, Sei Hyun Baik, Kwan Woo Lee, Moon Suk Nam, Yong Soo Park, Jeong Taek Woo, Young Seol Kim, Sunmin Park, So-Young Park, Chang Hoon Yim, Hyun Koo Yoon, Sung-Hoon Kim
Journal of Korean Medical Science.2014; 29(1): 84. CrossRef - Heart rate variability in children with type 1 diabetes mellitus
Camila Balsamo Gardim, Bruno Affonso P. de Oliveira, Aline Fernanda B. Bernardo, Rayana Loch Gomes, Francis Lopes Pacagnelli, Roselene Modolo R. Lorençoni, Luiz Carlos M. Vanderlei
Revista Paulista de Pediatria.2014; 32(2): 279. CrossRef - Development of an HbA1c-Based Conversion Equation for Estimating Glycated Albumin in a Korean Population with a Wide Range of Glucose Intolerance
Chang Hee Jung, You-Cheol Hwang, Kwang Joon Kim, Bong Soo Cha, Cheol-Young Park, Won Seon Jeon, Jae Hyeon Kim, Sang-Man Jin, Sang Youl Rhee, Jeong-taek Woo, Byung-Wan Lee, Sompop Bencharit
PLoS ONE.2014; 9(4): e95729. CrossRef - It's Still Not Too Late to Make a Change: Current Status of Glycemic Control in Korea
Sang Yong Kim
Diabetes & Metabolism Journal.2014; 38(3): 194. CrossRef - Prevalence and factors associated with diabetic retinopathy in a Korean adult population: The 2008–2009 Korea National Health and Nutrition Examination Survey
Ju Yean Yang, Na Kyung Kim, Yun Jeong Lee, Jung Hyun Noh, Dae Jung Kim, Kyung Soo Ko, Byoung Doo Rhee, Dong-Jun Kim
Diabetes Research and Clinical Practice.2013; 102(3): 218. CrossRef - Increasing achievement of the target goals for glycemic, blood pressure and lipid control for adults with diagnosed diabetes in Korea
Sung Hoon Yu, Jun Goo Kang, Yoo‐Cheol Hwang, Kyu Jeung Ahn, Hyung Joon Yoo, Hong Yup Ahn, Sung Woo Park, Cheol‐Young Park
Journal of Diabetes Investigation.2013; 4(5): 460. CrossRef - Hemoglobin A1c May Be an Inadequate Diagnostic Tool for Diabetes Mellitus in Anemic Subjects
Jung Il Son, Sang Youl Rhee, Jeong-taek Woo, Jin Kyung Hwang, Sang Ouk Chin, Suk Chon, Seungjoon Oh, Sung Woon Kim, Young Seol Kim
Diabetes & Metabolism Journal.2013; 37(5): 343. CrossRef - Implication of circulating omentin-1 level on the arterial stiffening in type 2 diabetes mellitus
Hye Jin Yoo, Soon Young Hwang, Ho Cheol Hong, Hae Yoon Choi, Sae Jeong Yang, Kwan Woo Lee, Moon Suk Nam, Yong Soo Park, Jeong Taek Woo, Young Seol Kim, Kyung Mook Choi, Sei Hyun Baik
Endocrine.2013; 44(3): 680. CrossRef - Comparison of Two Creatinine-Based Equations for Predicting Decline in Renal Function in Type 2 Diabetic Patients with Nephropathy in a Korean Population
Eun Young Lee, Young-Mi Lee, Kyu Hun Choi, Hyun Chul Lee, Byung-Wan Lee, Beom Seok Kim
International Journal of Endocrinology.2013; 2013: 1. CrossRef - Association between Nutrient Intake and Obesity in Type 2 Diabetic Patients from the Korean National Diabetes Program: A Cross-Sectional Study
So Hun Kim, Seong Bin Hong, Young Ju Suh, Yun Jin Choi, Moonsuk Nam, Hyoung Woo Lee, Ie Byung Park, Suk Chon, Jeong-Taek Woo, Sei Hyun Baik, Yongsoo Park, Dae Jung Kim, Kwan Woo Lee, Young Seol Kim
Journal of Korean Medical Science.2012; 27(10): 1188. CrossRef - C1q/TNF-Related Protein-3 (CTRP-3) and Pigment Epithelium-Derived Factor (PEDF) Concentrations in Patients With Type 2 Diabetes and Metabolic Syndrome
Kyung Mook Choi, Soon Young Hwang, Ho Cheol Hong, Sae Jeong Yang, Hae Yoon Choi, Hye Jin Yoo, Kwan Woo Lee, Moon Suk Nam, Yong Soo Park, Jeong Taek Woo, Young Seol Kim, Dong Seop Choi, Byung-Soo Youn, Sei Hyun Baik
Diabetes.2012; 61(11): 2932. CrossRef - Direct Medical Costs for Patients with Type 2 Diabetes and Related Complications: A Prospective Cohort Study Based on the Korean National Diabetes Program
Tae Ho Kim, Ki Hong Chun, Hae Jin Kim, Seung Jin Han, Dae Jung Kim, Jiyeong Kwak, Young Seol Kim, Jeong Taek Woo, Yongsoo Park, Moonsuk Nam, Sei Hyun Baik, Kyu Jeung Ahn, Kwan Woo Lee
Journal of Korean Medical Science.2012; 27(8): 876. CrossRef - Epidemiology of Micro- and Macrovascular Complications of Type 2 Diabetes in Korea
Jung Hee Kim, Dae Jung Kim, Hak Chul Jang, Sung Hee Choi
Diabetes & Metabolism Journal.2011; 35(6): 571. CrossRef - Letter: The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital (Diabetes Metab J 2011;35:543-50)
Won Jun Kim, Cheol-Young Park
Diabetes & Metabolism Journal.2011; 35(6): 637. CrossRef - Satisfaction with High Deductible Policies among Patients with Diabetes in the Korean General/University Hospital System
Dae Jung Kim
Journal of Korean Diabetes.2011; 12(4): 179. CrossRef
- Impact of diabetes distress on glycemic control and diabetic complications in type 2 diabetes mellitus
- Comparison of the Efficacy of Glimepiride, Metformin, and Rosiglitazone Monotherapy in Korean Drug-Naïve Type 2 Diabetic Patients: The Practical Evidence of Antidiabetic Monotherapy Study
- Kun Ho Yoon, Jeong Ah Shin, Hyuk Sang Kwon, Seung Hwan Lee, Kyung Wan Min, Yu Bae Ahn, Soon Jib Yoo, Kyu Jeung Ahn, Sung Woo Park, Kwan Woo Lee, Yeon Ah Sung, Tae Sun Park, Min Seon Kim, Yong Ki Kim, Moon Suk Nam, Hye Soon Kim, Ie Byung Park, Jong Suk Park, Jeong Taek Woo, Ho Young Son
- Diabetes Metab J. 2011;35(1):26-33. Published online February 28, 2011
- DOI: https://doi.org/10.4093/dmj.2011.35.1.26
- 55,923 View
- 86 Download
- 31 Crossref
-
Abstract
PDFPubReader
Background Although many anti-diabetic drugs have been used to control hyperglycemia for decades, the efficacy of commonly-used oral glucose-lowering agents in Korean type 2 diabetic patients has yet to be clearly demonstrated.
Methods We evaluated the efficacy of glimepiride, metformin, and rosiglitazone as initial treatment for drug-naïve type 2 diabetes mellitus patients in a 48-week, double-blind, randomized controlled study that included 349 Korean patients. Our primary goal was to determine the change in HbA1c levels from baseline to end point. Our secondary goal was to evaluate changes in fasting plasma glucose (FPG) levels, body weight, frequency of adverse events, and the proportion of participants achieving target HbA1c levels.
Results HbA1c levels decreased from 7.8% to 6.9% in the glimepiride group (
P <0.001), from 7.9% to 7.0% in the metformin group (P <0.001), and from 7.8% to 7.0% (P <0.001) in the rosiglitazone group. Glimepiride and rosiglitazone significantly increased body weight and metformin reduced body weight during the study period. Symptomatic hypoglycemia was more frequent in the glimepiride group and diarrhea was more frequent in the metformin group.Conclusion The efficacy of glimepiride, metformin, and rosiglitazone as antidiabetic monotherapies in drug-naïve Korean type 2 diabetic patients was similar in the three groups, with no statistical difference. This study is the first randomized controlled trial to evaluate the efficacy of commonly-used oral hypoglycemic agents in Korean type 2 diabetic patients. An additional subgroup analysis is recommended to obtain more detailed information.
-
Citations
Citations to this article as recorded by- Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial
Shebani Sethi, Diane Wakeham, Terence Ketter, Farnaz Hooshmand, Julia Bjornstad, Blair Richards, Eric Westman, Ronald M Krauss, Laura Saslow
Psychiatry Research.2024; 335: 115866. CrossRef - 2023 Clinical Practice Guidelines for Diabetes Mellitus of the Korean Diabetes Association
Jong Han Choi, Kyung Ae Lee, Joon Ho Moon, Suk Chon, Dae Jung Kim, Hyun Jin Kim, Nan Hee Kim, Ji A Seo, Mee Kyoung Kim, Jeong Hyun Lim, YoonJu Song, Ye Seul Yang, Jae Hyeon Kim, You-Bin Lee, Junghyun Noh, Kyu Yeon Hur, Jong Suk Park, Sang Youl Rhee, Hae J
Diabetes & Metabolism Journal.2023; 47(5): 575. CrossRef - The forgotten type 2 diabetes mellitus medicine: rosiglitazone
Bo Xu, Aoxiang Xing, Shuwei Li
Diabetology International.2022; 13(1): 49. CrossRef - Real-world comparison of mono and dual combination therapies of metformin, sulfonylurea, and dipeptidyl peptidase-4 inhibitors using a common data model
Kyung Ae Lee, Heung Yong Jin, Yu Ji Kim, Sang Soo Kim, Eun-Hee Cho, Tae Sun Park
Medicine.2022; 101(8): e28823. CrossRef - 2021 Clinical Practice Guidelines for Diabetes Mellitus of the Korean Diabetes Association
Kyu Yeon Hur, Min Kyong Moon, Jong Suk Park, Soo-Kyung Kim, Seung-Hwan Lee, Jae-Seung Yun, Jong Ha Baek, Junghyun Noh, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Ye Seul Yang, Jang Won Son, Jong Han Choi, Kee Ho Song, Nam Hoon Kim, Sang Yong Kim, Jin Wha Kim,
Diabetes & Metabolism Journal.2021; 45(4): 461. CrossRef - A RANDOMISED, PROSPECTIVE, PARALLELAND OPEN LABEL STUDY TO COMPARE EFFICACY AND SAFETY OF METFORMIN PLUS ROSUVASTATIN AND GLIMEPIRIDE PLUS ROSUVASTATIN IN PATIENTS OF COEXISTING NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND TYPE 2 DIABETES MELLITUS (T2DM)
Prabhsimran kaur, Gurpreet Kaur Randhawa, Surinder Kumar Salwan
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH.2021; : 46. CrossRef - Impact of sitagliptin combination therapy and hypoglycemia in Japanese patients with type 2 diabetes: a multi-center retrospective observational cohort study
Tomoyuki Saito, Hirotoshi Ohmura, Shuko Nojiri, Hiroyuki Daida
Journal of Pharmaceutical Health Care and Sciences.2020;[Epub] CrossRef - 2019 Clinical Practice Guidelines for Type 2 Diabetes Mellitus in Korea
Mee Kyoung Kim, Seung-Hyun Ko, Bo-Yeon Kim, Eun Seok Kang, Junghyun Noh, Soo-Kyung Kim, Seok-O Park, Kyu Yeon Hur, Suk Chon, Min Kyong Moon, Nan-Hee Kim, Sang Yong Kim, Sang Youl Rhee, Kang-Woo Lee, Jae Hyeon Kim, Eun-Jung Rhee, SungWan Chun, Sung Hoon Yu
Diabetes & Metabolism Journal.2019; 43(4): 398. CrossRef - Oral Hypoglycemic Agents for Patients with Type 2 Diabetes Mellitus
Seung-Hyun Ko
The Journal of Korean Diabetes.2019; 20(3): 142. CrossRef - Monotherapy in Type 2 Diabetes Mellitus Patients 2017: A Position Statement of the Korean Diabetes Association
Sang Youl Rhee
The Journal of Korean Diabetes.2018; 19(1): 15. CrossRef - Failure of monotherapy in clinical practice in patients with type 2 diabetes: The Korean National Diabetes Program
Ja Young Jeon, Soo Jin Lee, Sieun Lee, Soo Jin Kim, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Young Seol Kim, Jeong Taek Woo, Kyu Jeung Ahn, Moonsuk Nam, Sei Hyun Baik, Yongsoo Park, Kwan‐Woo Lee
Journal of Diabetes Investigation.2018; 9(5): 1144. CrossRef - Women are less likely than men to achieve optimal glycemic control after 1 year of treatment: A multi-level analysis of a Korean primary care cohort
Seung-Ah Choe, Joo Yeong Kim, Young Sun Ro, Sung-Il Cho, Antonio Palazón-Bru
PLOS ONE.2018; 13(5): e0196719. CrossRef - Monotherapy in Patients with Type 2 Diabetes Mellitus
Sang Youl Rhee, Hyun Jin Kim, Seung-Hyun Ko, Kyu-Yeon Hur, Nan-Hee Kim, Min Kyong Moon, Seok-O Park, Byung-Wan Lee, Kyung Mook Choi, Jin Hwa Kim
Diabetes & Metabolism Journal.2017; 41(5): 349. CrossRef - Antihyperglycemic Agent Therapy for Adult Patients with Type 2 Diabetes Mellitus 2017: A Position Statement of the Korean Diabetes Association
Seung-Hyun Ko, Kyu-Yeon Hur, Sang Youl Rhee, Nan-Hee Kim, Min Kyong Moon, Seok-O Park, Byung-Wan Lee, Hyun Jin Kim, Kyung Mook Choi, Jin Hwa Kim
Diabetes & Metabolism Journal.2017; 41(5): 337. CrossRef - Monotherapy in patients with type 2 diabetes mellitus
Sang Youl Rhee, Hyun Jin Kim, Seung-Hyun Ko, Kyu Yeon Hur, Nan-Hee Kim, Min Kyong Moon, Seok-O Park, Byung-Wan Lee, Kyung Mook Choi, Jin Hwa Kim
The Korean Journal of Internal Medicine.2017; 32(6): 959. CrossRef - Antihyperglycemic agent therapy for adult patients with type 2 diabetes mellitus 2017: a position statement of the Korean Diabetes Association
Seung-Hyun Ko, Kyu-Yeon Hur, Sang Youl Rhee, Nan-Hee Kim, Min Kyong Moon, Seok-O Park, Byung-Wan Lee, Hyun Jin Kim, Kyung Mook Choi, Jin Hwa Kim
The Korean Journal of Internal Medicine.2017; 32(6): 947. CrossRef - Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients
Jong-Dai Kim, Won-Young Lee
Endocrinology and Metabolism.2016; 31(3): 354. CrossRef - Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
Medicine.2016; 95(27): e4018. CrossRef - Clinical Practice Guideline 2015: Oral Hypoglycemic Agents for Patients with Type 2 Diabetes
Seung-Hyun Ko
The Journal of Korean Diabetes.2016; 17(2): 83. CrossRef - Efficacy and safety of teneligliptin, a dipeptidyl peptidase‐4 inhibitor, combined with metformin in Korean patients with type 2 diabetes mellitus: a 16‐week, randomized, double‐blind, placebo‐controlled phase III trial
M. K. Kim, E.‐J. Rhee, K. A. Han, A. C. Woo, M.‐K. Lee, B. J. Ku, C. H. Chung, K.‐A. Kim, H. W. Lee, I. B. Park, J. Y. Park, H. C. Chul Jang, K. S. Park, W. I. Jang, B. Y. Cha
Diabetes, Obesity and Metabolism.2015; 17(3): 309. CrossRef - Effect of Yanggyuksanhwa-Tang on non-insulin-dependent diabetes mellitus unresponsive to oral hypoglycemic agents: A case report
Jiman Kim, Seungwon Kwon
Chinese Journal of Integrative Medicine.2015; 21(2): 157. CrossRef - Efficacy of glimepiride/metformin fixed‐dose combination vs metformin uptitration in type 2 diabetic patients inadequately controlled on low‐dose metformin monotherapy: A randomized, open label, parallel group, multicenter study in Korea
Hye‐soon Kim, Doo‐man Kim, Bong‐soo Cha, Tae Sun Park, Kyoung‐ah Kim, Dong‐lim Kim, Choon Hee Chung, Jeong‐hyun Park, Hak Chul Jang, Dong‐seop Choi
Journal of Diabetes Investigation.2014; 5(6): 701. CrossRef - Evaluation of the Association between the Use of Oral Anti-hyperglycemic Agents and Hypoglycemia in Japan by Data Mining of the Japanese Adverse Drug Event Report (JADER) Database
Ryogo Umetsu, Yuri Nishibata, Junko Abe, Yukiya Suzuki, Hideaki Hara, Hideko Nagasawa, Yasutomi Kinosada, Mitsuhiro Nakamura
YAKUGAKU ZASSHI.2014; 134(2): 299. CrossRef - Comparative efficacy of glimepiride and metformin in monotherapy of type 2 diabetes mellitus: meta-analysis of randomized controlled trials
Hongmei Zhu, Shuang Zhu, Xiuqian Zhang, Yang Guo, Yunzhen Shi, Zhimin Chen, Siu-wai Leung
Diabetology & Metabolic Syndrome.2013;[Epub] CrossRef - A Comparative Study of the Effects of a Dipeptidyl Peptidase-IV Inhibitor and Sulfonylurea on Glucose Variability in Patients with Type 2 Diabetes with Inadequate Glycemic Control on Metformin
Hun-Sung Kim, Jeong-Ah Shin, Seung-Hwan Lee, Eun-Sook Kim, Jae-Hyoung Cho, Ho-Young Son, Kun-Ho Yoon
Diabetes Technology & Therapeutics.2013; 15(10): 810. CrossRef - Glycemic Effectiveness of Metformin-Based Dual-Combination Therapies with Sulphonylurea, Pioglitazone, or DPP4-Inhibitor in Drug-Naïve Korean Type 2 Diabetic Patients
Young Ki Lee, Sun Ok Song, Kwang Joon Kim, Yongin Cho, Younjeong Choi, Yujung Yun, Byung-Wan Lee, Eun-Seok Kang, Bong Soo Cha, Hyun Chul Lee
Diabetes & Metabolism Journal.2013; 37(6): 465. CrossRef - Metformin Based Dual-Combination Therapies in Drug Naïve Type 2 Diabetic Patients
Dong-Lim Kim
Diabetes & Metabolism Journal.2013; 37(6): 429. CrossRef - Assessing Relative Bioactivity of Chemical Substances Using Quantitative Molecular Network Topology Analysis
Anna Edberg, Daniel Soeria-Atmadja, Jonas Bergman Laurila, Fredrik Johansson, Mats G. Gustafsson, Ulf Hammerling
Journal of Chemical Information and Modeling.2012; 52(5): 1238. CrossRef - Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double‐blind, placebo‐controlled study
Ji Won Yoon, Seon Mee Kang, Jason L Vassy, Hayley Shin, Yun Hee Lee, Hwa Young Ahn, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Soo Lim
Journal of Diabetes Investigation.2012; 3(3): 309. CrossRef - What Is the Optimal Monotherapy in Korean Drug-Naïve Type 2 Diabetic Patients?: The Practical Evidence of Antidiabetic Monotherapy Study
Ji Hun Choi, Won-Young Lee
Diabetes & Metabolism Journal.2011; 35(1): 23. CrossRef - Predictive characteristics of patients achieving glycaemic control with insulin after sulfonylurea failure
Y.-H. Lee, B.-W. Lee, S. W. Chun, B. S. Cha, H. C. Lee
International Journal of Clinical Practice.2011; 65(10): 1076. CrossRef
- Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial
- Effect of Valsartan on Blood Pressure and Urinary Albumin Excretion in Hypertensive Type 2 Diabetic Patients: An Open-Label, Multicenter Study.
- Se Jun Park, Dae Jung Kim, Hae Jin Kim, Soo Yeon Park, Ji A Seo, Nan Hee Kim, Sung Hee Choi, Soo Lim, Hak Chul Jang, Seung Hyun Ko, Ki Ho Song, Yu Bae Ahn, Soo Kyoung Kim, Yong Wook Cho, Jun Goo Kang, Sung Hee Ihm, Cheol Young Park, Sung Woo Park, Dong Hyun Shin, Yong Hyun Kim, Kwan Woo Lee
- Korean Diabetes J. 2008;32(6):513-521. Published online December 1, 2008
- DOI: https://doi.org/10.4093/kdj.2008.32.6.513
- 2,297 View
- 25 Download
-
Abstract
PDF
- BACKGROUND
Activation of renin-angiotensin system (RAS) has been an important mechanism of microvascular and macrovascular complications in diabetic patients. It has been reported that RAS blockades reduce the development and progression of diabetic nephropathy. The aim of this study was to evaluate whether valsartan, an angiotensin II receptor blocker (ARB), reduced blood pressure and urinary albumin excretion rate (UAER) in hypertensive type 2 diabetic patients. METHOD: Three hundred forty-seven hypertensive type 2 diabetic patients who had not taken angiotensin converting enzyme inhibitors or ARB for 6 months prior to this study were enrolled. We measured blood pressure and UAER before and after 24 weeks of valsartan treatment. RESULT: Baseline mean systolic and diastolic blood pressure was 143 +/- 15 and 87 +/- 11 mmHg, respectively and the median albumin excretion rate was 27 ug/mg. Reduction in systolic and diastolic blood pressure was 16 mmHg/10 mmHg and the median UAER was 19.3 ug/mg after 24 weeks (P < 0.01, respectively). When we divided the subjects into three groups according to the UAER (normoalbuminuria, microalbuminuria and macroalbuminuria), significant changes were reported in the microalbuminuria and the macroalbuminuria groups. Thirty-eight (42%) patients with microalbuminuria improved to normoalbuminuria and twelve (41%) patients with macroalbuminuria improved to microalbuminuria. We found an association between the improvement of blood pressure and UAER (R = 0.165, P = 0.015). CONCLUSION: We concluded that valsartan reduces urinary albumin excretion and blood pressure in hypertensive type 2 diabetic patients.
- An Analysis of Medical Costs of Diabetic Patients in a University Hospital (1996~2005).
- Ki Hong Chun, Kwan Woo Lee, Dae Jung Kim, Hae Jin Kim, Kyung Won Paek, Soo Jin Lee
- Korean Diabetes J. 2008;32(4):366-376. Published online August 1, 2008
- DOI: https://doi.org/10.4093/kdj.2008.32.4.366
- 2,251 View
- 19 Download
- 2 Crossref
-
Abstract
PDF
- BACKGROUND
The aim of this research was to find out the costs of diabetes, as research in a prospective cohort study looking into the development of diabetic complications followed by treatment intervention by a medical institution. The research compared the changes in medical costs by following-up on the treatment details of diagnosed diabetes for the last 10 years in a university hospital. METHODS: The research used data of outpatient, inpatient, pharmaceutical and total medical costs, from 1996 to 2005, of individual patients who were diagnosed with diabetic patients, to analyze the outpatient and inpatient total medical cost changes over the years. RESULTS: After antidiabetic drug, in the case of outpatient treatment, pharmaceutical costs increased on average by about 25,000 won a month for diabetic patients without complications and by 35,000 won for diabetic patients with microvascular complications. Outpatient medical costs were affected after drug treatment by as much of an increase as created by the pharmaceutical costs. The total medical costs, that is the sum of inpatient and outpatient costs, decreased by 30~40% compared to that before drug treatment. In the case of total medical cost, MI or ESRD cost 2~3 times more in pharmaceutical costs than before the development of complications. The total medical costs of diabetic patients with CVA, MI and ESRD complications increased in the first year after development of the complication, and this was followed by a decrease in the next year, showing a tendency to remain constant with no increase or decrease over subsequent years. This means that the total medical costs of patients with complications remain continuously large throughout the life of the diagnosed patient. CONCLUSION: For diabetic patients, pharmaceutical costs are the most important factor in determining outpatient medical costs. -
Citations
Citations to this article as recorded by
- Clinical Characteristics and Direct Medical Costs of Type 2 Diabetic Patients.
- Eun Joon Moon, Young Eun Jo, Tae Chin Park, Yun Kyung Kim, Sun Hye Jung, Hae Jin Kim, Dae Jung Kim, Yoon Sok Chung, Kwan Woo Lee
- Korean Diabetes J. 2008;32(4):358-365. Published online August 1, 2008
- DOI: https://doi.org/10.4093/kdj.2008.32.4.358
- 2,429 View
- 37 Download
- 15 Crossref
-
Abstract
PDF
- BACKGROUND
Type 2 diabetes mellitus is an expensive chronic metabolic disorder and its prevalence has been increasing rapidly in South Korea, owing to a westernized lifestyle. We analyzed the annual direct medical costs attributable to type 2 diabetes and its chronic complications in Korea retrospectively. METHODS: We randomly selected 1,051 patients with type 2 diabetes who visited Ajou University Hospital as an outpatient in 2005. Clinical characteristics, duration of diabetes, and microvascular and macrovascular complications were assessed from a medical chart review. The annual direct medical costs included insurance covered and uncovered medical costs. RESULTS: Of the 1,051 patients with type 2 diabetes, 48.2% had at least one microvascular complication, 5.6% had at least one macrovascular complication, and 12.4% of the patients had both microvascular and macrovascular complications. The average annual direct medical cost was found to be 3,348,488won per patient. In patients with microvascular complications, the total cost of management was increased 1.4 times compared to those without complications. Direct medical costs for patients with macrovascular complications were 2.1-fold as high as patients with no complications. Those patients with both microvascular and macrovascular complications, increased costs by 3.1-fold over those without complications. CONCLUSION: Chronic complications have a substantial impact on the direct medical costs of type 2 diabetes. The prevention of chronic diabetic complications will not only influence the mortality and morbidity of patients with type 2 diabetes, but also potentially reduce medical costs. -
Citations
Citations to this article as recorded by- Importance of family history of diabetes in computing a diabetes risk score in Korean prediabetic population
Morena Ustulin, Sang Youl Rhee, Suk Chon, Kyu Keung Ahn, Ji Eun Lim, Bermseok Oh, Sung-Hoon Kim, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Young Seol Kim, Jeong-Taek Woo
Scientific Reports.2018;[Epub] CrossRef - Features of Long-Standing Korean Type 2 Diabetes Mellitus Patients with Diabetic Retinopathy: A Study Based on Standardized Clinical Data
Sejeong Park, Sang Youl Rhee, Su Jin Jeong, Kiyoung Kim, Suk Chon, Seung-Young Yu, Jeong-Taek Woo
Diabetes & Metabolism Journal.2017; 41(5): 393. CrossRef - Association between Sleep Duration and Impaired Fasting Glucose in Korean Adults: Results from the Korean National Health and Nutrition Examination Survey 2011–2012
Cho-Rong Kim, Yun-Mi Song, Jin-Young Shin, Wook Gim
Korean Journal of Family Medicine.2016; 37(1): 51. CrossRef - Trends in the Diabetes Epidemic in Korea
Kyoung Hwa Ha, Dae Jung Kim
Endocrinology and Metabolism.2015; 30(2): 142. CrossRef - Economic Evaluation of Diabetes Education
Jin-Won Noh, Young Dae Kwon, Jin-Hee Jung, Kang Hee Sim, Hee-Sook Kim, Minjae Choi, Jumin Park
The Journal of Korean Diabetes.2015; 16(4): 293. CrossRef - Association between diabetes-related factors and clinical periodontal parameters in type-2 diabetes mellitus
Eun-Kyong Kim, Sang Gyu Lee, Youn-Hee Choi, Kyu-Chang Won, Jun Sung Moon, Anwar T Merchant, Hee-Kyung Lee
BMC Oral Health.2013;[Epub] CrossRef - Cytoprotective Effect of Ethanol Extract from Maesil (Prunus mume Sieb. et Zucc.) on Alloxan-induced Oxidative Damage in Pancreatic-cell, HIT-T15
In-Hye Kim, Jong-Bae Kim, Kang-Jin Cho, Jae-Hyun Kim, Ae-Son Om
Korean Journal of Plant Resources.2012; 25(2): 184. CrossRef - The Protective Effects of Chrysanthemum cornarium L. var. spatiosum Extract on HIT-T15 Pancreatic β-Cells against Alloxan-induced Oxidative Stress
In-Hye Kim, Kang-Jin Cho, Jeong-Sook Ko, Jae-Hyun Kim, Ae-Son Om
The Korean Journal of Food And Nutrition.2012; 25(1): 123. CrossRef - Outcome Research in Diabetes
Kwan Woo Lee
Journal of Korean Diabetes.2011; 12(1): 2. CrossRef - Costs of Diabetes Mellitus in Korea
Kwan Woo Lee
Diabetes & Metabolism Journal.2011; 35(6): 567. CrossRef - The Epidemiology of Diabetes in Korea
Dae Jung Kim
Diabetes & Metabolism Journal.2011; 35(4): 303. CrossRef - The Hypoglycemic Effect of Complex of Chinese Traditional Herbs (CTH) and Macelignan in Type 2 Diabetic Animal Model
Journal of Life Science.2010; 20(7): 1113. CrossRef - Epidemiologic Characteristics of Diabetes Mellitus in Korea: Current Status of Diabetic Patients Using Korean Health Insurance Database
Ie Byung Park, Sei Hyun Baik
Korean Diabetes Journal.2009; 33(5): 357. CrossRef - Management of Diabetic Mellitus in Low-income Rural Patients
Hye-Yeon Kim, Woo-Jun Yun, Min-Ho Shin, Sun-Seong Kweon, Hye-Ran Ahn, Seong-Woo Choi, Young-Hoon Lee, Dong-Hyeok Cho, Jung-Ae Rhee
Journal of Preventive Medicine and Public Health.2009; 42(5): 315. CrossRef - Prevalence of Pancreatic Cancer in Diabetics and Clinical Characteristics of Diabetes-associated with Pancreatic Cancer - Comparison between Diabetes with and without Pancreatic Cancer -
Seung Goun Hong, Jae Seon Kim, Sung Joo Jung, Moon Kyung Joo, Beom Jae Lee, Jong Eun Yeon, Jong-Jae Park, Kwan Soo Byun, Young-Tae Bak
The Korean Journal of Gastroenterology.2009; 54(3): 167. CrossRef
- Importance of family history of diabetes in computing a diabetes risk score in Korean prediabetic population
- A Study on Resistance in Type 2 Diabetic Patient Against Commencement of Insulin Treatment.
- Sun Hwa Hong, Mi Jin Kim, Sung Gab Noh, Dae Won Suh, Suk Jung Youn, Kwan Woo Lee, Ho Chae Lee, Yang Soo Chung, Hong Ryang Chung, Hyuk Sang Kwon, Bong Yun Cha, Ho Young Son, Kun Ho Yoon
- Korean Diabetes J. 2008;32(3):269-279. Published online June 1, 2008
- DOI: https://doi.org/10.4093/kdj.2008.32.3.269
- 2,356 View
- 48 Download
- 8 Crossref
-
Abstract
PDF
- BACKGROUND
To achieve tight glycemic control in the poorly controlled type 2 diabetic patients with oral hypoglycemic agent, it maybe beneficial to initiate insulin treatment at the early stage. Many patients with type 2 diabetes are often reluctant to begin insulin therapy despite poor glycemic control with oral hypoglycemic agents, this little known phenomenon, often termed 'psychological insulin resistance (PIR)'. This study investigates psychological insulin resistance in Korean patients with type 2 diabetes. METHOD: This study examined a total of 76 type 2 diabetic patients with poor glycemic control during period of April to July 2006. Through questionnaire and telephone survey, total 24 questions were asked about various attitudes on insulin therapy including psychological barriers and patients' acceptance of this treatment. Subjects were asked to allocate points in 5-point scale (from 5 points for 'very true' to 1 point for 'very untrue'). RESULTS: The means of psychological rejection, injection-related anxiety and fear of insulin side effects such as hypoglycemia and weight gain were 3.65 +/- 0.92, 3.17 +/- 0.98 and 2.8 +/- 1.02, respectively. Unwillingness was common in insulin therapy, 67% of patient rejected or was unwilling to take insulin. Main reasons of patients most frequently endorsed beginning insulin indicate that disease is worsening, permanence (once you start insulin you can never quit) and sense of personal failure. Furthermore, study indicates that patients' reasons for avoiding insulin therapy were mainly psychological rejection, which extended far beyond a simple injection related anxiety. CONCLUSION: PIR was psychological reluctance rather than injection related anxiety. To overcome these psychological barriers to insulin treatment, it is necessary to address appropriate diabetes education including training and counseling with excellent interactive communications between patients and clinicians. -
Citations
Citations to this article as recorded by- Using Motivational Interviewing to Overcome Psychological Insulin Resistance
Sung-Chul Lim
The Journal of Korean Diabetes.2023; 24(4): 227. CrossRef - Psychological Insulin Resistance: Key Factors and Intervention
Yeon Jeong Jang
The Journal of Korean Diabetes.2021; 22(3): 192. CrossRef - Factors influencing psychological insulin resistance in type 2 diabetes patients
Ji Hyeon Yu, Hye Young Kim, Sung Reul Kim, Eun Ko, Heung Yong Jin
International Journal of Nursing Practice.2019;[Epub] CrossRef - Development of a Psychological Insulin Resistance Scale for Korean Patients with Diabetes
Youngshin Song, Younghee Jeon, Jeonghwa Cho, Bohyun Kim
Journal of Korean Academy of Nursing.2016; 46(6): 813. CrossRef - Patients' perspectives on taking insulin in diabetes - Perspectives of convergence
Youngshin Song, Eunkyong Ah
Journal of Digital Convergence.2016; 14(12): 283. CrossRef - Concept Analysis for Psychological Insulin Resistance in Korean People with Diabetes
Youngshin Song
Journal of Korean Academy of Nursing.2016; 46(3): 443. CrossRef - New Insulin Injection Recommendations
Min Jeong Gu
The Journal of Korean Diabetes.2016; 17(4): 261. CrossRef - Glucose, Blood Pressure, and Lipid Control in Korean Adults with Diagnosed Diabetes
Sun-Joo Boo
Korean Journal of Adult Nursing.2012; 24(4): 406. CrossRef
- Using Motivational Interviewing to Overcome Psychological Insulin Resistance
- Direct Medical Costs of Type 2 Diabetic Patients in the Tertiary Hospital.
- Joo An Hwang, Tae Chin Park, Sun Hye Jung, Hae Jin Kim, Dae Jung Kim, So Hun Kim, Moon Suk Nam, Tae Hyun Kim, Moon Kyu Lee, Kwan Woo Lee
- Korean Diabetes J. 2008;32(3):259-268. Published online June 1, 2008
- DOI: https://doi.org/10.4093/kdj.2008.32.3.259
- 2,215 View
- 31 Download
- 8 Crossref
-
Abstract
PDF
- BACKGROUND
Type 2 diabetes mellitus is a common, chronic and costly disease. Its prevalence is rapidly increasing worldwide. Diabetes has big economic burden mainly because of its chronic complications. We analyzed the annual direct medical costs of type 2 diabetic patients, including the costs associated with its complications in Korea retrospectively. METHODS: We enrolled 531 type 2 diabetic patients who had been treated in the 3 Tertiary Hospital in 2005. Clinical characteristics, duration of diabetes, modality of glycemic control, and presence of microvascular and macrovascular complications were assessed by the review of medical records. The annual direct medical costs were assessed using the hospital electronic database and included insurance covered and uncovered medical costs. RESULTS: The annual direct medical costs of type 2 diabetic patients without any complications was 1,184,563 won (95% CI for mean: 973,006~1,396,121 won). Compared to diabetic patients without complications, annual total medical costs increased 4.7-fold, 10.7-fold, and 8.8-fold in patients with microvascular complications, macrovascular complications and both complications, respectively. Hospitalization costs largely increased by 78.7-fold and 61.0-fold in patients with macrovascular complications and both complications, respectively. Major complications to increase medical costs were kidney transplantation (23.1-fold), dialysis (21.0-fold), PTCA or CABG (12.4-fold), and leg amputation (11.8-fold). The total medical costs dramatically increased according to the stage of diabetic retinopathy and nephropathy. CONCLUSION: Diabetic complications have a substantial impact on the direct medical costs of type 2 diabetic patients. The prevention of diabetic complications will benefit the patients as well as the overall healthcare expenditures. -
Citations
Citations to this article as recorded by- Policy Proposals for Infection Control in Patients with Chronic Wounds
Kyung-Chul Moon, Donghyeok Shin, Kyu-Won Baek, Changsik John Pak, Young-Joon Jun
Journal of Wound Management and Research.2022; 18(3): 249. CrossRef - Effects of Co‐administration of Sulfonylureas and Antimicrobial Drugs on Hypoglycemia in Patients with Type 2 Diabetes Using a Case‐Crossover Design
Sera Lee, Miyoung Ock, Hun‐Sung Kim, Hyunah Kim
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy.2020; 40(9): 902. CrossRef - The effect of continuity of care on the incidence of end-stage renal disease in patients with newly detected type 2 diabetic nephropathy: a retrospective cohort study
Yun Jung Jang, Yoon Soo Choy, Chung Mo Nam, Ki Tae Moon, Eun-Cheol Park
BMC Nephrology.2018;[Epub] CrossRef - Social Welfare Information for Patients with Diabetes Mellitus
Jea Yeon Lee
The Journal of Korean Diabetes.2016; 17(2): 117. CrossRef - Hypoglycemia and Health Costs
Yong-ho Lee, Gyuri Kim, Eun Seok Kang
The Journal of Korean Diabetes.2016; 17(1): 11. CrossRef - Outcome Research in Diabetes
Kwan Woo Lee
Journal of Korean Diabetes.2011; 12(1): 2. CrossRef - Costs of Diabetes Mellitus in Korea
Kwan Woo Lee
Diabetes & Metabolism Journal.2011; 35(6): 567. CrossRef - How Much Amount of Socioeconomic Loss Is Caused by Digestive Diseases?
Kyung Sik Park
The Korean Journal of Gastroenterology.2011; 58(6): 297. CrossRef
- Policy Proposals for Infection Control in Patients with Chronic Wounds
- Clinical Characteristics of Korean Type 2 Diabetic Patients According to Insulin Secretion and Insulin Resistance.
- Kyoung Eun Song, Dae Jung Kim, Ji Won Park, Hong Keun Cho, Kwan Woo Lee, Kap Bum Huh
- Korean Diabetes J. 2007;31(2):123-129. Published online March 1, 2007
- DOI: https://doi.org/10.4093/jkda.2007.31.2.123
- 2,041 View
- 36 Download
- 10 Crossref
-
Abstract
PDF
- BACKGROUND
Korean type 2 diabetic patients are known to differ from western diabetes because of their unique characteristics, such as non-obese but centrally obese anthropometry and relatively more insulin secretory defects than insulin resistance compared to western diabetic patients. METHODS: We recruited 1,646 diabetic patients in the present study and excluded the 45 patients with fasting C-peptide < 0.20 nmol/L. We had assessed insulin secretion by fasting serum C-peptide level and insulin resistance by short insulin tolerance test (Kitt ; rate constant for plasma glucose disappearance, %/min) in the private diabetes clinic. The insulin secretory defect was divided by severe (C-peptide < 0.37 nmol/L), moderate (C-peptide 0.37~0.56 nmol/L), and normal (C-peptide > or = 0.57 nmol/L) group. The insulin resistance was divided by insulin resistant (IR) (Kitt < 2.5 %/min) and insulin sensitive (IS) (Kitt > or = 2.5 %/min) group. RESULTS: We analysed the data of 1,601 type 2 diabetic patients (831 men and 770 women, age 56.5 +/- 10.8 years, duration of diabetes 9.6 +/- 7.3 years). The prevalence of BMI > or = 25.0 kg/m2 is 42.5% and BMI > or = 23.0 kg/m2 is 70.2%. The prevalence of abdominal obesity (waist > or = 90 cm in men and 80 cm in women) is 45.2% (36.0% and 55.2%, respectively in men and women). Fasting C-peptide level is 0.64 +/- 0.29 nmol/L and Kitt value is 2.03 +/- 0.96%/min. According to fasting C-peptide level, the degree of insulin secretory defect were severe (13.1%), moderate (33.0%) and normal (53.9%). According to Kitt value, the IR group is 70.6% and the IS group is 29.4%. CONCLUSION: Obese type 2 diabetes is markedly increasing in Korea. Therefore, the major problem in Korean type 2 diabetic patients is being changed into insulin resistance instead of insulin secretory defect. -
Citations
Citations to this article as recorded by- Effect of Euonymus alatus Extracts on Diabetes Related Markers in Pancreatic β-Cells and C57BL/Ksj-db/db Mice
Ye Rin Kim, Eun-young Kim, Seong Uk Lee, Young Wan Kim, Yoon Hee Kim
Journal of the Korean Society of Food Science and Nutrition.2022; 51(9): 894. CrossRef - Effect of Nutrition Counseling by Nutrition Care Process on Diet Therapy Practice and Glycemic Control in Type 2 Diabetic Patients
Tae-Jeong Bae, Na-Eun Jeon, Soo-Kyong Choi, Jung-Sook Seo
Korean Journal of Community Nutrition.2020; 25(3): 214. CrossRef - Calpain-10 and Adiponectin Gene Polymorphisms in Korean Type 2 Diabetes Patients
Ji Sun Nam, Jung Woo Han, Sang Bae Lee, Ji Hong You, Min Jin Kim, Shinae Kang, Jong Suk Park, Chul Woo Ahn
Endocrinology and Metabolism.2018; 33(3): 364. CrossRef - Obesity and Insulin Resistance According to Age in Newly Diagnosed Type 2 Diabetes Patients in Korea
Ju Won Lee, Nam Kyu Kim, Hyun Joon Park, Jun Yeob Lee, Seon Yoon Choi, Eun Mi Lee, So Young Ock, Su Kyoung Kwon, Young Sik Choi, Bu Kyung Kim
Kosin Medical Journal.2016; 31(2): 157. CrossRef - The Insulin Resistance but Not the Insulin Secretion Parameters Have Changed in the Korean Population during the Last Decade
Hae Kyung Yang, Jin Hee Lee, In-Young Choi, Hyuk Sang Kwon, Jeong Ah Shin, Seung Hee Jeong, Seung-Hwan Lee, Jae Hyoung Cho, Ho Young Son, Kun Ho Yoon
Diabetes & Metabolism Journal.2015; 39(2): 117. CrossRef - The Effects of Low-Calorie Diets on Abdominal Visceral Fat, Muscle Mass, and Dietary Quality in Obese Type 2 Diabetic Subjects (Korean Diabetes J 2009;33:526-36)
Hee-Jung Ahn, Kyung-Wan Min
Korean Diabetes Journal.2010; 34(1): 68. CrossRef - Effects ofSasa BorealisLeaf Extract on the Glucose Tolerance of Major Foods for Carbohydrate
Eun-Kyoung Yun, Young-Ran Heo, Hyeon-Sook Lim
The Korean Journal of Nutrition.2010; 43(3): 215. CrossRef - The Effects of Low-Calorie Diets on Abdominal Visceral Fat, Muscle Mass, and Dietary Quality in Obese Type 2 Diabetic Subjects (Korean Diabetes J 2009;33:526-36)
Won-Young Lee
Korean Diabetes Journal.2010; 34(1): 66. CrossRef - Anti-GAD Antibody in Patients with Adult-Onset Diabetes in Korea
Eun-Gyoung Hong
Korean Diabetes Journal.2009; 33(1): 13. CrossRef - Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats
Hyejin Jeong, Hye Jin Kwon, Mi Kyung Kim
Nutrition Research and Practice.2009; 3(1): 23. CrossRef
- Effect of Euonymus alatus Extracts on Diabetes Related Markers in Pancreatic β-Cells and C57BL/Ksj-db/db Mice
Randomized Controlled Trial
- Comparison of the Efficacy and Safety of Glimepiride/Metformin Fixed Combination Versus Free Combination in Patients with Type 2 Diabetes: Multicenter, Randomized, Controlled Trial.
- Seung Hwan Lee, In Kyu Lee, Sei Hyun Baik, Dong Seop Choi, Kyong Soo Park, Ki Ho Song, Kwan Woo Lee, Bong Soo Cha, Chul Woo Ahn, Hyoung Woo Lee, Choon Hee Chung, Moon Suk Nam, Hong Sun Baek, Yong Ki Kim, Hyo Young Rhim, Ho Young Son
- Korean Diabetes J. 2006;30(6):466-475. Published online November 1, 2006
- DOI: https://doi.org/10.4093/jkda.2006.30.6.466
- 2,308 View
- 35 Download
- 2 Crossref
-
Abstract
PDF
- BACKGROUND
Failure to manage diabetes mellitus receiving monotherapy increases as the duration of the disease is protracted, and in many cases it becomes inevitable to introduce combined therapies. However, compliance of the patients tends to decrease. We conducted a clinical study to compare the efficacy and safety of preconstituted and fixed combination therapy of glimepiride plus metformin to those of free combination therapy. METHODS: Two hundred and thirteen patients with type 2 diabetes who had been diagnosed at least six months ago were randomly assigned either to a fixed group or a free group. The initial dosage was chosen according to the previous treatment history and then adjusted every two weeks following a predefined titration algorithm to meet the target mean fasting glucose levels (140 mg/dL). The medications were given for 16 weeks. The primary endpoint was the change in HbA1c level from baseline to week 16. Various parameters were checked as secondary outcome measures and safety criteria. RESULTS: HbA1c level of the fixed group and the free group decreased by 1.09% and 1.08%, respectively. The 95% CI of the changes' difference between the two groups (-0.21%, +0.19%) was within the predefined equivalence interval (-0.5%, +0.5%). Secondary outcome measures (the changes of fasting and postprandial plasma glucose level, response rate and compliance) and safety criteria (frequency of hypoglycemia and adverse reactions) were similar between the two groups. CONCLUSION: Fixed combination of glimepiride/metformin is as effective and safe therapy as free combination in type 2 diabetes patients. -
Citations
Citations to this article as recorded by- Efficacy and safety of glimepiride/metformin sustained release once daily vs. glimepiride/metformin twice daily in patients with type 2 diabetes
Y.-C. Hwang, M. Kang, C. W. Ahn, J. S. Park, S. H. Baik, D. J. Chung, H. C. Jang, K.-A. Kim, I.-K. Lee, K. W. Min, M. Nam, T. S. Park, S. M. Son, Y.-A. Sung, J.-T. Woo, K. S. Park, M.-K. Lee
International Journal of Clinical Practice.2013; 67(3): 236. CrossRef - Pharmacokinetic comparison of a new glimepiride 1-mg + metformin 500-mg combination tablet formulation and a glimepiride 2-mg + metformin 500-mg combination tablet formulation: A single-dose, randomized, open-label, two-period, two-way crossover study in
Bo-Hyung Kim, Kwang-Hee Shin, JaeWoo Kim, Kyoung Soo Lim, Kyu-pyo Kim, Jung-Ryul Kim, Joo-Youn Cho, Sang-Goo Shin, In-Jin Jang, Kyung-Sang Yu
Clinical Therapeutics.2009; 31(11): 2755. CrossRef
- Efficacy and safety of glimepiride/metformin sustained release once daily vs. glimepiride/metformin twice daily in patients with type 2 diabetes
Original Article
- Efficacy Evaluation of Atorvastatin in Korean Hyperlipidemic Patients with Type 2 Diabetes Mellitus.
- Dong Seop Choi, Duk Kyu Kim, Doo Man Kim, Seong Yeon Kim, Moon Suk Nam, Yong Soo Park, Ho Sang Shon, Chul Woo Ahn, Kwan Woo Lee, Ki Up Lee, Moon Kyu Lee, Choon Hee Chung, Bong Yeon Cha
- Korean Diabetes J. 2006;30(4):292-302. Published online July 1, 2006
- DOI: https://doi.org/10.4093/jkda.2006.30.4.292
- 2,081 View
- 20 Download
- 3 Crossref
-
Abstract
PDF
- BACKGROUND
NCEP ATP III Guideline recommends aggressive treatments of diabetic dyslipidemia, recognizing diabetes mellitus as CHD risk equivalents. This study was conducted to evaluate the effectiveness and safety of atorvastatin in hyperlipidemic patients with Type 2 diabetes mellitus through post-marketing drug use investigation of atorvastatin. METHODS: An open, multi-center, non-comparison, titrated dosage study was conducted in hyperlipidemic patients, who were treated with atorvastatin at first visiting hospitals from Mar. 2004 to Sep. 2004. 96 endocrinologists participated from 66 centers in this study. Total 2,182 hyperlipidemic patients were enrolled and 1,514 patients among them were accompanied by diabetes mellitus. Efficacy was evaluated at later than 4-week treatment by % change of total cholesterol, triglycerides, HDL-cholesterol and LDL-cholesterol from baseline. Percent of patients reaching LDL-cholesterol level less than 100 mg/dL was also analyzed. The adverse events incidence and abnormalities of clinical laboratory values were evaluated for safety monitoring. RESULTS: Total cholesterol, triglycerides, and LDL-cholesterol level were reduced by 26.6%, 12.0%, and 34.8%, respectively, in diabetic hyperlipidemic patients after atorvastatin treatment. The patients with LDL-cholesterol level of less than 100 mg/dL were increased from 2.8% to 52.6%. Atorvastatin was considered to be safe because adverse drug reactions were reported in 32 patients (1.5%) of total 2,182 patients. CONCLUSION: Atorvastatin was effective and safe in hyperlipidemic patients with type 2 diabetes mellitus. -
Citations
Citations to this article as recorded by- Response: A Retrospective Study on the Efficacy of a Ten-Milligram Dosage of Atorvastatin for Treatment of Hypercholesterolemia in Type 2 Diabetes Mellitus Patients (Korean Diabetes J 2010;34:359-67)
Dong Kyun Kim, Sa Rah Lee, Min Sik Kim, Suk Hyang Bae, Jin Yeon Hwang, Jung-Min Kim, Sung Hwan Suh, Hye-Jeong Lee, Mi Kyoung Park, Duk Kyu Kim
Diabetes & Metabolism Journal.2011; 35(1): 88. CrossRef - A Retrospective Study on the Efficacy of a Ten-Milligram Dosage of Atorvastatin for Treatment of Hypercholesterolemia in Type 2 Diabetes Mellitus Patients
Dong Kyun Kim, Sa Rah Lee, Min Sik Kim, Suk Hyang Bae, Jin Yeon Hwang, Jung-Min Kim, Sung Hwan Suh, Hye-Jeong Lee, Mi Kyoung Park, Duk Kyu Kim
Korean Diabetes Journal.2010; 34(6): 359. CrossRef - The Association of Plasma HDL-Cholesterol Level with Cardiovascular Disease Related Factors in Korean Type 2 Diabetic Patients
Hye Sook Hong, Jong Suk Park, Han Kyoung Ryu, Wha Young Kim
Korean Diabetes Journal.2008; 32(3): 215. CrossRef
- Response: A Retrospective Study on the Efficacy of a Ten-Milligram Dosage of Atorvastatin for Treatment of Hypercholesterolemia in Type 2 Diabetes Mellitus Patients (Korean Diabetes J 2010;34:359-67)
First
Prev
